1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas
The differentiation of solitary intra-axial hematomas from hemorrhagic neoplasms based on their magnetic resonance imaging (MRI) features is challenging. The treatment and prognosis for these two disease entities are vastly different and distinction between them is often based on MRI findings alone....
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-12-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2021.778320/full |
| _version_ | 1818966294436773888 |
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| author | James Whitlock Andrew Holdsworth Carles Morales Laurent Garosi Inés Carrera |
| author_facet | James Whitlock Andrew Holdsworth Carles Morales Laurent Garosi Inés Carrera |
| author_sort | James Whitlock |
| collection | DOAJ |
| description | The differentiation of solitary intra-axial hematomas from hemorrhagic neoplasms based on their magnetic resonance imaging (MRI) features is challenging. The treatment and prognosis for these two disease entities are vastly different and distinction between them is often based on MRI findings alone. The aim of this study was to describe the 1.5 tesla MRI features of canine intra-axial hematomas and correlate these findings with the evolution of hemorrhages described in human brains. Retrospective evaluation of patient details, clinical signs, and MRI findings of dogs with intra-axial hematomas that were histopathologically confirmed or determined via repeat MRI study and/or resolution of neurological signs. Ten dogs met the inclusion criteria. All 10 hematoma lesions were determined to be 2–7 days in age. On MRI, all 10 hemorrhagic lesions were comprised of two distinct regions; a relatively thin T1-weighted (T1W), T2-weighted (T2W) and gradient echo (GRE) hypointense (9/10) peripheral border region and a large central region that was heterogenous but predominantly T1W, T2W and GRE hyperintense (8/10). The peripheral border region was complete in its integrity in all 10 cases on T2W and GRE sequences. Contrast enhancement was present in (6/10) hematoma lesions and was always peripheral in nature with no evidence of central enhancement associated with any of the lesions. An intra-axial hematoma should be suspected in solitary hemorrhagic space occupying lesions that have a complete hypointense peripheral rim, elicit a peripheral contrast enhancement pattern, and display the expected temporal pattern of hematoma evolution. |
| first_indexed | 2024-12-20T13:30:37Z |
| format | Article |
| id | doaj.art-9007402afd884f08b8b197b57d87a071 |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-12-20T13:30:37Z |
| publishDate | 2021-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-9007402afd884f08b8b197b57d87a0712022-12-21T19:39:07ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692021-12-01810.3389/fvets.2021.7783207783201.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial HematomasJames Whitlock0Andrew Holdsworth1Carles Morales2Laurent Garosi3Inés Carrera4Willows Referral Centre, Part of Linnaeus Veterinary Limited, Solihull, United KingdomDavies Veterinary Specialists, Hitchin, United KingdomVet Oracle, Norfolk, United KingdomArs Veterinary Hospital, Barcelona, SpainWillows Referral Centre, Part of Linnaeus Veterinary Limited, Solihull, United KingdomThe differentiation of solitary intra-axial hematomas from hemorrhagic neoplasms based on their magnetic resonance imaging (MRI) features is challenging. The treatment and prognosis for these two disease entities are vastly different and distinction between them is often based on MRI findings alone. The aim of this study was to describe the 1.5 tesla MRI features of canine intra-axial hematomas and correlate these findings with the evolution of hemorrhages described in human brains. Retrospective evaluation of patient details, clinical signs, and MRI findings of dogs with intra-axial hematomas that were histopathologically confirmed or determined via repeat MRI study and/or resolution of neurological signs. Ten dogs met the inclusion criteria. All 10 hematoma lesions were determined to be 2–7 days in age. On MRI, all 10 hemorrhagic lesions were comprised of two distinct regions; a relatively thin T1-weighted (T1W), T2-weighted (T2W) and gradient echo (GRE) hypointense (9/10) peripheral border region and a large central region that was heterogenous but predominantly T1W, T2W and GRE hyperintense (8/10). The peripheral border region was complete in its integrity in all 10 cases on T2W and GRE sequences. Contrast enhancement was present in (6/10) hematoma lesions and was always peripheral in nature with no evidence of central enhancement associated with any of the lesions. An intra-axial hematoma should be suspected in solitary hemorrhagic space occupying lesions that have a complete hypointense peripheral rim, elicit a peripheral contrast enhancement pattern, and display the expected temporal pattern of hematoma evolution.https://www.frontiersin.org/articles/10.3389/fvets.2021.778320/fullMRIdoghemorrhageintracranialhematoma |
| spellingShingle | James Whitlock Andrew Holdsworth Carles Morales Laurent Garosi Inés Carrera 1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas Frontiers in Veterinary Science MRI dog hemorrhage intracranial hematoma |
| title | 1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas |
| title_full | 1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas |
| title_fullStr | 1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas |
| title_full_unstemmed | 1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas |
| title_short | 1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas |
| title_sort | 1 5 tesla magnetic resonance imaging features of canine intracranial intra axial hematomas |
| topic | MRI dog hemorrhage intracranial hematoma |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2021.778320/full |
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