Advances in the applications of biologics in the treatment of chronic spontaneous urticaria
Chronic spontaneous urticaria (CSU) is a common immune skin disease in clinic. Mast cells are the key effector cells in the pathogenesis of CSU. With the continuous understanding of the pathogenesis of CSU in recent years, many new biologics have been used to treat CSU. Biologics can effectively tre...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology
2024-02-01
|
| Series: | Pifu-xingbing zhenliaoxue zazhi |
| Subjects: | |
| Online Access: | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2024.02.012 |
| _version_ | 1797249356853673984 |
|---|---|
| author | Xuemei HUANG Shanshan OU Jiaoquan CHEN Hui ZOU Ziyan CHEN Weihong WU Hui WU Runxiang LI Huilan ZHU |
| author_facet | Xuemei HUANG Shanshan OU Jiaoquan CHEN Hui ZOU Ziyan CHEN Weihong WU Hui WU Runxiang LI Huilan ZHU |
| author_sort | Xuemei HUANG |
| collection | DOAJ |
| description | Chronic spontaneous urticaria (CSU) is a common immune skin disease in clinic. Mast cells are the key effector cells in the pathogenesis of CSU. With the continuous understanding of the pathogenesis of CSU in recent years, many new biologics have been used to treat CSU. Biologics can effectively treat CSU by targeting different stages of mast cell activation, blocking their activation and degranulation. According to the target and mechanisms of their action, biologics can be classified into inhibition of mast cell activation and intracellular signaling transduction, and activation of inhibitory receptor. This article will review the applications of biologics in the treatment of CSU. |
| first_indexed | 2024-04-24T20:29:11Z |
| format | Article |
| id | doaj.art-9009b3d9ab6843a09ff38633f4e44125 |
| institution | Directory Open Access Journal |
| issn | 1674-8468 |
| language | zho |
| last_indexed | 2024-04-24T20:29:11Z |
| publishDate | 2024-02-01 |
| publisher | editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology |
| record_format | Article |
| series | Pifu-xingbing zhenliaoxue zazhi |
| spelling | doaj.art-9009b3d9ab6843a09ff38633f4e441252024-03-22T02:47:14Zzhoeditoiral office of Journal of Diagnosis and Therapy on Dermato-venereologyPifu-xingbing zhenliaoxue zazhi1674-84682024-02-0131213614110.3969/j.issn.1674-8468.2024.02.012Advances in the applications of biologics in the treatment of chronic spontaneous urticariaXuemei HUANG0Shanshan OU1Jiaoquan CHEN2Hui ZOU3Ziyan CHEN4Weihong WU5Hui WU6Runxiang LI7Huilan ZHU8Guangzhou Institute of Dermatology, Guangzhou 510095, ChinaGuangzhou Institute of Dermatology, Guangzhou 510095, ChinaGuangzhou Institute of Dermatology, Guangzhou 510095, ChinaGuangzhou Institute of Dermatology, Guangzhou 510095, ChinaGuangzhou Institute of Dermatology, Guangzhou 510095, ChinaGuangzhou Institute of Dermatology, Guangzhou 510095, ChinaGuangzhou Institute of Dermatology, Guangzhou 510095, ChinaGuangzhou Institute of Dermatology, Guangzhou 510095, ChinaGuangzhou Institute of Dermatology, Guangzhou 510095, ChinaChronic spontaneous urticaria (CSU) is a common immune skin disease in clinic. Mast cells are the key effector cells in the pathogenesis of CSU. With the continuous understanding of the pathogenesis of CSU in recent years, many new biologics have been used to treat CSU. Biologics can effectively treat CSU by targeting different stages of mast cell activation, blocking their activation and degranulation. According to the target and mechanisms of their action, biologics can be classified into inhibition of mast cell activation and intracellular signaling transduction, and activation of inhibitory receptor. This article will review the applications of biologics in the treatment of CSU.http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2024.02.012chronic spontaneous urticariabiologicstreatment |
| spellingShingle | Xuemei HUANG Shanshan OU Jiaoquan CHEN Hui ZOU Ziyan CHEN Weihong WU Hui WU Runxiang LI Huilan ZHU Advances in the applications of biologics in the treatment of chronic spontaneous urticaria Pifu-xingbing zhenliaoxue zazhi chronic spontaneous urticaria biologics treatment |
| title | Advances in the applications of biologics in the treatment of chronic spontaneous urticaria |
| title_full | Advances in the applications of biologics in the treatment of chronic spontaneous urticaria |
| title_fullStr | Advances in the applications of biologics in the treatment of chronic spontaneous urticaria |
| title_full_unstemmed | Advances in the applications of biologics in the treatment of chronic spontaneous urticaria |
| title_short | Advances in the applications of biologics in the treatment of chronic spontaneous urticaria |
| title_sort | advances in the applications of biologics in the treatment of chronic spontaneous urticaria |
| topic | chronic spontaneous urticaria biologics treatment |
| url | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2024.02.012 |
| work_keys_str_mv | AT xuemeihuang advancesintheapplicationsofbiologicsinthetreatmentofchronicspontaneousurticaria AT shanshanou advancesintheapplicationsofbiologicsinthetreatmentofchronicspontaneousurticaria AT jiaoquanchen advancesintheapplicationsofbiologicsinthetreatmentofchronicspontaneousurticaria AT huizou advancesintheapplicationsofbiologicsinthetreatmentofchronicspontaneousurticaria AT ziyanchen advancesintheapplicationsofbiologicsinthetreatmentofchronicspontaneousurticaria AT weihongwu advancesintheapplicationsofbiologicsinthetreatmentofchronicspontaneousurticaria AT huiwu advancesintheapplicationsofbiologicsinthetreatmentofchronicspontaneousurticaria AT runxiangli advancesintheapplicationsofbiologicsinthetreatmentofchronicspontaneousurticaria AT huilanzhu advancesintheapplicationsofbiologicsinthetreatmentofchronicspontaneousurticaria |