Comparison between Target Sample Check Illuminator and White Light Observation in Discriminating the Presence of Target Specimen for Endoscopic Ultrasound-Guided Fine Needle Aspiration Sample
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is an essential endoscopic tissue sampling method for diagnosing pancreatobiliary diseases; however, determining the presence of target specimens mixed in the blood by conventional observation is challenging due to the small size of the o...
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MDPI AG
2023-03-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/6/2139 |
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| author | Hiroki Koda Kazuya Matsumoto Soichiro Kawata Yohei Takeda Takumi Onoyama Yuta Seki Yuri Sakamoto Takuya Shimosaka Wataru Hamamoto Taro Yamashita Hiroki Kurumi Naoyuki Yamaguchi Hisashi Noma Hajime Isomoto |
| author_facet | Hiroki Koda Kazuya Matsumoto Soichiro Kawata Yohei Takeda Takumi Onoyama Yuta Seki Yuri Sakamoto Takuya Shimosaka Wataru Hamamoto Taro Yamashita Hiroki Kurumi Naoyuki Yamaguchi Hisashi Noma Hajime Isomoto |
| author_sort | Hiroki Koda |
| collection | DOAJ |
| description | Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is an essential endoscopic tissue sampling method for diagnosing pancreatobiliary diseases; however, determining the presence of target specimens mixed in the blood by conventional observation is challenging due to the small size of the obtained sample. This study investigated the usefulness of a target sample check illuminator (TSCI) that emits a specific wavelength of light to determine the presence of target specimens. Twenty-seven patients who underwent EUS-FNA at our hospital were included. Conventional white light observation was performed for the collected samples, followed by TSCI; six people evaluated the presence of the target specimen on a 5-point scale. The target specimen discrimination score using TSCI (median: 5) was significantly higher than that using conventional white light observation (median: 1) (<i>p</i> < 0.001). No significant difference was observed in the discrimination score between the evaluator (novice vs. expert, <i>p</i> = 0.162) and puncture needle (22G vs. 25G, <i>p</i> = 0.196). The discriminability of TSCI in the samples obtained using EUS-FNA was significantly higher than that of conventional observation. TSCI does not depend on the evaluator or puncture needle for the identification of the target specimen; hence, it can provide a good pathological specimen and may contribute to the improvement of the diagnostic ability. |
| first_indexed | 2024-03-11T06:23:12Z |
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| id | doaj.art-900dd5ac946d49bca0c2428b67b6d808 |
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| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T06:23:12Z |
| publishDate | 2023-03-01 |
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| series | Journal of Clinical Medicine |
| spelling | doaj.art-900dd5ac946d49bca0c2428b67b6d8082023-11-17T11:48:39ZengMDPI AGJournal of Clinical Medicine2077-03832023-03-01126213910.3390/jcm12062139Comparison between Target Sample Check Illuminator and White Light Observation in Discriminating the Presence of Target Specimen for Endoscopic Ultrasound-Guided Fine Needle Aspiration SampleHiroki Koda0Kazuya Matsumoto1Soichiro Kawata2Yohei Takeda3Takumi Onoyama4Yuta Seki5Yuri Sakamoto6Takuya Shimosaka7Wataru Hamamoto8Taro Yamashita9Hiroki Kurumi10Naoyuki Yamaguchi11Hisashi Noma12Hajime Isomoto13Department of Gastroenterology, Tottori University Hospital, Yonago 683-8504, JapanDepartment of Gastroenterology, Tottori University Hospital, Yonago 683-8504, JapanDepartment of Gastroenterology, Tottori University Hospital, Yonago 683-8504, JapanDepartment of Gastroenterology, Tottori University Hospital, Yonago 683-8504, JapanDepartment of Gastroenterology, Tottori University Hospital, Yonago 683-8504, JapanDepartment of Gastroenterology, Tottori University Hospital, Yonago 683-8504, JapanDepartment of Gastroenterology, Tottori University Hospital, Yonago 683-8504, JapanDepartment of Gastroenterology, Tottori University Hospital, Yonago 683-8504, JapanDepartment of Gastroenterology, Tottori University Hospital, Yonago 683-8504, JapanDepartment of Gastroenterology, Tottori University Hospital, Yonago 683-8504, JapanDepartment of Gastroenterology, Tottori University Hospital, Yonago 683-8504, JapanDepartment of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biological Sciences, Nagasaki 852-8501, JapanDepartment of Data Science, The Institute of Statistical Mathematics, Tachikawa 190-8562, JapanDepartment of Gastroenterology, Tottori University Hospital, Yonago 683-8504, JapanEndoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is an essential endoscopic tissue sampling method for diagnosing pancreatobiliary diseases; however, determining the presence of target specimens mixed in the blood by conventional observation is challenging due to the small size of the obtained sample. This study investigated the usefulness of a target sample check illuminator (TSCI) that emits a specific wavelength of light to determine the presence of target specimens. Twenty-seven patients who underwent EUS-FNA at our hospital were included. Conventional white light observation was performed for the collected samples, followed by TSCI; six people evaluated the presence of the target specimen on a 5-point scale. The target specimen discrimination score using TSCI (median: 5) was significantly higher than that using conventional white light observation (median: 1) (<i>p</i> < 0.001). No significant difference was observed in the discrimination score between the evaluator (novice vs. expert, <i>p</i> = 0.162) and puncture needle (22G vs. 25G, <i>p</i> = 0.196). The discriminability of TSCI in the samples obtained using EUS-FNA was significantly higher than that of conventional observation. TSCI does not depend on the evaluator or puncture needle for the identification of the target specimen; hence, it can provide a good pathological specimen and may contribute to the improvement of the diagnostic ability.https://www.mdpi.com/2077-0383/12/6/2139target sample check illuminatorendoscopic ultrasound-guided fine needle aspirationendoscopic ultrasound-guided fine needle biopsyrapid on-site evaluationmacroscopic on-site quality evaluation |
| spellingShingle | Hiroki Koda Kazuya Matsumoto Soichiro Kawata Yohei Takeda Takumi Onoyama Yuta Seki Yuri Sakamoto Takuya Shimosaka Wataru Hamamoto Taro Yamashita Hiroki Kurumi Naoyuki Yamaguchi Hisashi Noma Hajime Isomoto Comparison between Target Sample Check Illuminator and White Light Observation in Discriminating the Presence of Target Specimen for Endoscopic Ultrasound-Guided Fine Needle Aspiration Sample Journal of Clinical Medicine target sample check illuminator endoscopic ultrasound-guided fine needle aspiration endoscopic ultrasound-guided fine needle biopsy rapid on-site evaluation macroscopic on-site quality evaluation |
| title | Comparison between Target Sample Check Illuminator and White Light Observation in Discriminating the Presence of Target Specimen for Endoscopic Ultrasound-Guided Fine Needle Aspiration Sample |
| title_full | Comparison between Target Sample Check Illuminator and White Light Observation in Discriminating the Presence of Target Specimen for Endoscopic Ultrasound-Guided Fine Needle Aspiration Sample |
| title_fullStr | Comparison between Target Sample Check Illuminator and White Light Observation in Discriminating the Presence of Target Specimen for Endoscopic Ultrasound-Guided Fine Needle Aspiration Sample |
| title_full_unstemmed | Comparison between Target Sample Check Illuminator and White Light Observation in Discriminating the Presence of Target Specimen for Endoscopic Ultrasound-Guided Fine Needle Aspiration Sample |
| title_short | Comparison between Target Sample Check Illuminator and White Light Observation in Discriminating the Presence of Target Specimen for Endoscopic Ultrasound-Guided Fine Needle Aspiration Sample |
| title_sort | comparison between target sample check illuminator and white light observation in discriminating the presence of target specimen for endoscopic ultrasound guided fine needle aspiration sample |
| topic | target sample check illuminator endoscopic ultrasound-guided fine needle aspiration endoscopic ultrasound-guided fine needle biopsy rapid on-site evaluation macroscopic on-site quality evaluation |
| url | https://www.mdpi.com/2077-0383/12/6/2139 |
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