Drug-induced gingival overgrowth: A critical insight into case reports from over two decades
Drug-induced gingival overgrowth (DIGO) is a well-recognized adverse effect of certain systemic medications. Calcium channel blockers, anticonvulsants, and immunosuppressants are frequently implicated drugs in the etiology of DIGO. Drug variables, plaque-induced inflammation, and genetic factors are...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Journal of Indian Society of Periodontology |
| Subjects: | |
| Online Access: | http://www.jisponline.com/article.asp?issn=0972-124X;year=2016;volume=20;issue=5;spage=496;epage=502;aulast=Samudrala |
| _version_ | 1819111673288458240 |
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| author | Pramod Samudrala Vijay Kumar Chava Tanguturi Sri Chandana Rachakonda Suresh |
| author_facet | Pramod Samudrala Vijay Kumar Chava Tanguturi Sri Chandana Rachakonda Suresh |
| author_sort | Pramod Samudrala |
| collection | DOAJ |
| description | Drug-induced gingival overgrowth (DIGO) is a well-recognized adverse effect of certain systemic medications. Calcium channel blockers, anticonvulsants, and immunosuppressants are frequently implicated drugs in the etiology of DIGO. Drug variables, plaque-induced inflammation, and genetic factors are the three important factors in the expression of gingival changes after systemic medication use. Careful clinical examination and thorough history taking form the basis for diagnosis of DIGO. Histopathological examination is often neglected; however, it is an important aid that helps in differential diagnosis. Cessation or change of drug and meticulous plaque control often leads to regression of the lesion, which however might need surgical correction for optimal maintenance of gingival health. The purpose of the present article is to review case reports and case series published in the last two decades and to assimilate and compile the information for clinical applications such as diagnosis and therapeutic management of DIGO. |
| first_indexed | 2024-12-22T04:01:21Z |
| format | Article |
| id | doaj.art-901234b347834cc0aaa573fa7bc9b35e |
| institution | Directory Open Access Journal |
| issn | 0972-124X |
| language | English |
| last_indexed | 2024-12-22T04:01:21Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Society of Periodontology |
| spelling | doaj.art-901234b347834cc0aaa573fa7bc9b35e2022-12-21T18:39:45ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Periodontology0972-124X2016-01-0120549650210.4103/jisp.jisp_265_15Drug-induced gingival overgrowth: A critical insight into case reports from over two decadesPramod SamudralaVijay Kumar ChavaTanguturi Sri ChandanaRachakonda SureshDrug-induced gingival overgrowth (DIGO) is a well-recognized adverse effect of certain systemic medications. Calcium channel blockers, anticonvulsants, and immunosuppressants are frequently implicated drugs in the etiology of DIGO. Drug variables, plaque-induced inflammation, and genetic factors are the three important factors in the expression of gingival changes after systemic medication use. Careful clinical examination and thorough history taking form the basis for diagnosis of DIGO. Histopathological examination is often neglected; however, it is an important aid that helps in differential diagnosis. Cessation or change of drug and meticulous plaque control often leads to regression of the lesion, which however might need surgical correction for optimal maintenance of gingival health. The purpose of the present article is to review case reports and case series published in the last two decades and to assimilate and compile the information for clinical applications such as diagnosis and therapeutic management of DIGO.http://www.jisponline.com/article.asp?issn=0972-124X;year=2016;volume=20;issue=5;spage=496;epage=502;aulast=SamudralaAnticonvulsantscalcium channel blockersdental plaquedrug-induced gingival overgrowthgenetic factorsimmunosuppressantsoral hygiene |
| spellingShingle | Pramod Samudrala Vijay Kumar Chava Tanguturi Sri Chandana Rachakonda Suresh Drug-induced gingival overgrowth: A critical insight into case reports from over two decades Journal of Indian Society of Periodontology Anticonvulsants calcium channel blockers dental plaque drug-induced gingival overgrowth genetic factors immunosuppressants oral hygiene |
| title | Drug-induced gingival overgrowth: A critical insight into case reports from over two decades |
| title_full | Drug-induced gingival overgrowth: A critical insight into case reports from over two decades |
| title_fullStr | Drug-induced gingival overgrowth: A critical insight into case reports from over two decades |
| title_full_unstemmed | Drug-induced gingival overgrowth: A critical insight into case reports from over two decades |
| title_short | Drug-induced gingival overgrowth: A critical insight into case reports from over two decades |
| title_sort | drug induced gingival overgrowth a critical insight into case reports from over two decades |
| topic | Anticonvulsants calcium channel blockers dental plaque drug-induced gingival overgrowth genetic factors immunosuppressants oral hygiene |
| url | http://www.jisponline.com/article.asp?issn=0972-124X;year=2016;volume=20;issue=5;spage=496;epage=502;aulast=Samudrala |
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