Insulin signaling in skeletal muscle during inflammation and/or immobilisation

Insulin signaling in skeletal muscle during inflammation and/or immobilisation

Abstract Background The decline in the downstream signal transduction pathway of anabolic hormone, insulin, could play a key role in the muscle atrophy and insulin resistance observed in patients with intensive care unit acquired weakness (ICUAW). This study investigated the impact of immobilisation...

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Bibliographic Details
Main Authors: Julius J. Grunow, Thomas Gan, Heidrun Lewald, J. A. Jeevendra Martyn, Manfred Blobner, Stefan J. Schaller
Format: Article
Language:English
Published: SpringerOpen 2023-03-01
Series:Intensive Care Medicine Experimental
Subjects:
Intensive care unit acquired weakness
Immobilisation
Inflammation
Muscle atrophy
Insulin signaling
Online Access:https://doi.org/10.1186/s40635-023-00503-9

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