Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo

Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo

T regulatory (Treg) cells play vital roles in modulating immunity and tissue homeostasis. Their actions depend on TCR recognition of peptide-MHC molecules; yet the degree of peptide specificity of Treg-cell function, and whether Treg ligands can be used to manipulate Treg cell biology are unknown. H...

Podrobná bibliografie
Hlavní autoři:	Ricardo A Fernandes, Chaoran Li, Gang Wang, Xinbo Yang, Christina S Savvides, Caleb R Glassman, Shen Dong, Eric Luxenberg, Leah V Sibener, Michael E Birnbaum, Christophe Benoist, Diane Mathis, K Christopher Garcia
Médium:	Článek
Jazyk:	English
Vydáno:	eLife Sciences Publications Ltd 2020-08-01
Edice:	eLife
Témata:	inflammation Treg cells adipose tissue surrogate antigens
On-line přístup:	https://elifesciences.org/articles/58463

Podobné jednotky

Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo
Autor: Fernandes, Ricardo A, a další
Vydáno: (2021)

Do natural Treg become activated to antigen specific Treg in transplantation and in autoimmunity?
Autor: Bruce Milne Hall, a další
Vydáno: (2013-08-01)

Regulation of Treg Cell Metabolism and Function in Non-Lymphoid Tissues
Autor: Kai Yang, a další
Vydáno: (2022-06-01)

Difference between CD25+Tregs and Helios+Tregs in a murine model of allergic rhinitis
Autor: Yun-Xiu Wang, a další
Vydáno: (2021-09-01)

Tissue Treg Secretomes and Transcription Factors Shared With Stem Cells Contribute to a Treg Niche to Maintain Treg-Ness With 80% Innate Immune Pathways, and Functions of Immunosuppression and Tissue Repair
Autor: Ruijing Zhang, a další
Vydáno: (2021-02-01)

Mini-Review: Tregs as a Tool for Therapy—Obvious and Non-Obvious Challenges and Solutions
Autor: Elena I. Morgun, a další
Vydáno: (2024-10-01)

Immunosuppressive Treg cells acquire the phenotype of effector-T cells in chronic lymphocytic leukemia patients
Autor: Serena De Matteis, a další
Vydáno: (2018-06-01)

Surrogate motherhood
Autor: Arteta-Acosta Cindy
Vydáno: (2011-06-01)

CAR-T Regulatory (CAR-Treg) Cells: Engineering and Applications
Autor: Motahareh Arjomandnejad, a další
Vydáno: (2022-01-01)

The immunomodulation role of Th17 and Treg in renal transplantation
Autor: Dan-Lei Huang, a další
Vydáno: (2023-02-01)

IMMUNOLOGICAL MEMORY: THE ROLE OF REGULATORY CELLS (TREGS)
Autor: E. K. Oleinik, a další
Vydáno: (2018-11-01)

Adipose Tissue Immunomodulation and Treg/Th17 Imbalance in the Impaired Glucose Metabolism of Children with Obesity
Autor: Stefania Croce, a další
Vydáno: (2021-06-01)

Selecting the Best Quantity and Variety of Surrogates for an Ensemble Model
Autor: Pengcheng Ye, a další
Vydáno: (2020-10-01)

Prognostic values of regulatory T cells (Tregs) and Treg-related genes in gastric cancer
Autor: Liang Zheng, a další
Vydáno: (2023-04-01)

Role of Regulatory T Cells (Treg) and the Treg Effector Molecule Fibrinogen-like Protein 2 in Alloimmunity and Autoimmunity
Autor: Andrzej Chruscinski, a další
Vydáno: (2015-07-01)

ICOS+ Tregs: A Functional Subset of Tregs in Immune Diseases
Autor: Dan-Yang Li, a další
Vydáno: (2020-08-01)

Association of surrogate adiposity markers with prevalence, all-cause mortality and long-term survival of heart failure: a retrospective study from NHANES database
Autor: Fan-Shun Guo, a další
Vydáno: (2025-03-01)

Editorial: Inflammatory Treg reprogramming in the tumor immune microenvironment
Autor: Xinpei Deng, a další
Vydáno: (2024-04-01)

‘Repair’ Treg Cells in Tissue Injury
Autor: Chaoqi Zhang, a další
Vydáno: (2017-10-01)

Legal Regulation of Surrogate Maternity
Autor: Tsvetkov V. A.
Vydáno: (2012-11-01)

Investigation of the Molecular Evolution of Treg Suppression Mechanisms Indicates a Convergent Origin
Autor: Suniti Bhaumik, a další
Vydáno: (2023-01-01)

Acid Sphingomyelinase (ASM) is a Negative Regulator of Regulatory T Cell (Treg) Development
Autor: Yuetao Zhou, a další
Vydáno: (2016-08-01)

Corrigendum: ICOS+ Tregs: A Functional Subset of Tregs in Immune Diseases
Autor: Dan-Yang Li, a další
Vydáno: (2021-05-01)

Incorporating Covariates into Measures of Surrogate Paradox Risk
Autor: Fatema Shafie Khorassani, a další
Vydáno: (2023-02-01)

Tregitopes Improve Asthma by Promoting Highly Suppressive and Antigen-Specific Tregs
Autor: Marieme Dembele, a další
Vydáno: (2021-04-01)

Altered Tregs and oxidative stress in pregnancy associated lupus
Autor: Naveet Pannu, a další
Vydáno: (2019-08-01)

Legal Nature of the Contract of Surrogate Mother
Autor: seyyed mohammad sadegh tabatabaei
Vydáno: (2014-12-01)

Molecular mechanisms of Treg-mediated T cell suppression
Autor: Angelika eSchmidt, a další
Vydáno: (2012-03-01)

Breast cancer tumor microenvironment affects Treg/IL-17-producing Treg/Th17 cell axis: Molecular and therapeutic perspectives
Autor: Farhad Seif, a další
Vydáno: (2023-03-01)

Treg-targeted efficient-inducible platform for collagen-induced arthritis treatment
Autor: Lin Wang, a další
Vydáno: (2023-04-01)

Outcomes of the toxic hepatites caused by alcohol surrogates
Autor: I. Yu. Pirogova, a další
Vydáno: (2013-12-01)

Role of CD4+CD25+FOXP3+ TReg cells on tumor immunity
Autor: Agustinus Darmadi Hariyanto, a další
Vydáno: (2021-09-01)

Surrogate-assisted evolutionary algorithms for expensive combinatorial optimization: a survey
Autor: Shulei Liu, a další
Vydáno: (2024-05-01)

Human trafficking and surrogate motherhood: challenges
Autor: Viktor Checherskiy
Vydáno: (2021-11-01)

Sustained store-operated calcium entry utilizing activated chromatin state leads to instability in iTregs
Autor: Huiyun Lyu, a další
Vydáno: (2023-12-01)

Recipient Tregs: Can They Be Exploited for Successful Hematopoietic Stem Cell Transplant Outcomes?
Autor: Sabrina N. Copsel, a další
Vydáno: (2022-06-01)

Surrogate utility estimation by long-term partners and unfamiliar dyads
Autor: Richard J Tunney, a další
Vydáno: (2015-03-01)

Ratio of Th17/Treg and Disease Activity in Systemic Lupus Erythematosus
Autor: Yuliasih Yuliasih, a další
Vydáno: (2019-01-01)

Using a Tolerance-based Surrogate Method for Computer Resources Saving in Optimization
Autor: M. Marek, a další
Vydáno: (2019-04-01)

Comparison of seven surrogate insulin resistance indexes for prediction of incident coronary heart disease risk: a 10-year prospective cohort study
Autor: Li Liu, a další
Vydáno: (2024-01-01)