DNA mismatch repair system regulates the expression of PD-L1 through DNMTs in cervical cancer

DNA mismatch repair system regulates the expression of PD-L1 through DNMTs in cervical cancer

Abstract Background Cervical cancer (CC) is a potential clinical application of PD-1/PD-L1 inhibitor. We aimed to study the mechanism of DNA mismatch repair (MMR) system regulating the expression of PD-L1 in CC through DNA methyltransferase (DNMTs). Methods We collected pathological specimens from 1...

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Bibliographic Details
Main Authors:	Fan Guo, Ruijiao Lu, Weina Kong, Miyessar Anwar, Yangchun Feng
Format:	Article
Language:	English
Published:	BMC 2024-01-01
Series:	Cancer Cell International
Subjects:	Cervical cancer Programmed death-ligand 1 DNA mismatch repair
Online Access:	https://doi.org/10.1186/s12935-024-03214-7

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