Bridging Interpretability and Performance: Enhanced Machine Learning-Based Prediction of Hematoma Expansion Post-Stroke via Comprehensive Feature Selection

Monitoring and controlling the occurrence of hematoma expansion events after a stroke is a primary clinical focus. The introduction of machine learning (ML) techniques offers intelligent decision support for physicians in this domain. However, for doctors without an ML background, the behavior of a...

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Main Authors: Beigeng Zhao, Rui Song, Xu Guo, Lizhi Yu
Format: Article
Language:English
Published: IEEE 2024-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/10376172/
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author Beigeng Zhao
Rui Song
Xu Guo
Lizhi Yu
author_facet Beigeng Zhao
Rui Song
Xu Guo
Lizhi Yu
author_sort Beigeng Zhao
collection DOAJ
description Monitoring and controlling the occurrence of hematoma expansion events after a stroke is a primary clinical focus. The introduction of machine learning (ML) techniques offers intelligent decision support for physicians in this domain. However, for doctors without an ML background, the behavior of a hematoma expansion predictor seems opaque, similar to a “black box.” Moreover, the vast and diverse set of features typically present in medical data acts as a double-edged sword: while encapsulating rich information with potential value, it also includes redundant details that offer little to predictive utility. Comprehensive feature selection is crucial, but many current state-of-the-art hematoma expansion prediction studies based on ML often overlook this step. In this paper, we propose a methodology tailored for comprehensive feature selection across diverse and abundant medical data features and rigorously evaluate ML models. Through experiments on a real-world post-stroke hematoma expansion prediction dataset, we demonstrate the efficacy of our approach in enhancing the performance of ML predictors. Visualization of the associated feature selection process and results further bolsters physicians’ understanding of the model’s decision-making basis, thereby strengthening its interpretability.
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spelling doaj.art-902a298e50bd4f3ab576cc9c7db0180f2024-01-09T00:04:05ZengIEEEIEEE Access2169-35362024-01-01121688169910.1109/ACCESS.2023.334824410376172Bridging Interpretability and Performance: Enhanced Machine Learning-Based Prediction of Hematoma Expansion Post-Stroke via Comprehensive Feature SelectionBeigeng Zhao0Rui Song1Xu Guo2Lizhi Yu3College of Public Security Information Technology and Intelligence, Criminal Investigation Police University of China, Shenyang, ChinaCollege of Public Security Information Technology and Intelligence, Criminal Investigation Police University of China, Shenyang, ChinaDepartment of Neurosurgery, Liaoning Cancer Hospital and Institute, Shenyang, ChinaYuhong Sub-Bureau, Shenyang Public Security Bureau, Shenyang, ChinaMonitoring and controlling the occurrence of hematoma expansion events after a stroke is a primary clinical focus. The introduction of machine learning (ML) techniques offers intelligent decision support for physicians in this domain. However, for doctors without an ML background, the behavior of a hematoma expansion predictor seems opaque, similar to a “black box.” Moreover, the vast and diverse set of features typically present in medical data acts as a double-edged sword: while encapsulating rich information with potential value, it also includes redundant details that offer little to predictive utility. Comprehensive feature selection is crucial, but many current state-of-the-art hematoma expansion prediction studies based on ML often overlook this step. In this paper, we propose a methodology tailored for comprehensive feature selection across diverse and abundant medical data features and rigorously evaluate ML models. Through experiments on a real-world post-stroke hematoma expansion prediction dataset, we demonstrate the efficacy of our approach in enhancing the performance of ML predictors. Visualization of the associated feature selection process and results further bolsters physicians’ understanding of the model’s decision-making basis, thereby strengthening its interpretability.https://ieeexplore.ieee.org/document/10376172/Hematoma expansionpost-strokemachine learningfeature selectionmodel interpretability
spellingShingle Beigeng Zhao
Rui Song
Xu Guo
Lizhi Yu
Bridging Interpretability and Performance: Enhanced Machine Learning-Based Prediction of Hematoma Expansion Post-Stroke via Comprehensive Feature Selection
IEEE Access
Hematoma expansion
post-stroke
machine learning
feature selection
model interpretability
title Bridging Interpretability and Performance: Enhanced Machine Learning-Based Prediction of Hematoma Expansion Post-Stroke via Comprehensive Feature Selection
title_full Bridging Interpretability and Performance: Enhanced Machine Learning-Based Prediction of Hematoma Expansion Post-Stroke via Comprehensive Feature Selection
title_fullStr Bridging Interpretability and Performance: Enhanced Machine Learning-Based Prediction of Hematoma Expansion Post-Stroke via Comprehensive Feature Selection
title_full_unstemmed Bridging Interpretability and Performance: Enhanced Machine Learning-Based Prediction of Hematoma Expansion Post-Stroke via Comprehensive Feature Selection
title_short Bridging Interpretability and Performance: Enhanced Machine Learning-Based Prediction of Hematoma Expansion Post-Stroke via Comprehensive Feature Selection
title_sort bridging interpretability and performance enhanced machine learning based prediction of hematoma expansion post stroke via comprehensive feature selection
topic Hematoma expansion
post-stroke
machine learning
feature selection
model interpretability
url https://ieeexplore.ieee.org/document/10376172/
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AT ruisong bridginginterpretabilityandperformanceenhancedmachinelearningbasedpredictionofhematomaexpansionpoststrokeviacomprehensivefeatureselection
AT xuguo bridginginterpretabilityandperformanceenhancedmachinelearningbasedpredictionofhematomaexpansionpoststrokeviacomprehensivefeatureselection
AT lizhiyu bridginginterpretabilityandperformanceenhancedmachinelearningbasedpredictionofhematomaexpansionpoststrokeviacomprehensivefeatureselection