Multiple Eyelid Signs are Suggestive of Demodex Infestation
Lunla Udomwech, Nonthapan Phasuk School of Medicine, Walailak University, Nakhon Si Thammarat, ThailandCorrespondence: Lunla UdomwechSchool of Medicine, Walailak University, 222 Thaiburi, Tha Sala, Nakhon Si Thammarat, 80160, ThailandTel +6675 672 801Fax +6675 672 807Email lunla.ud@wu.ac.thPurpose:...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2021-02-01
|
| Series: | Clinical Ophthalmology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/multiple-eyelid-signs-are-suggestive-of-demodex-infestation-peer-reviewed-article-OPTH |
| _version_ | 1819195674675118080 |
|---|---|
| author | Udomwech L Phasuk N |
| author_facet | Udomwech L Phasuk N |
| author_sort | Udomwech L |
| collection | DOAJ |
| description | Lunla Udomwech, Nonthapan Phasuk School of Medicine, Walailak University, Nakhon Si Thammarat, ThailandCorrespondence: Lunla UdomwechSchool of Medicine, Walailak University, 222 Thaiburi, Tha Sala, Nakhon Si Thammarat, 80160, ThailandTel +6675 672 801Fax +6675 672 807Email lunla.ud@wu.ac.thPurpose: To determine the signs associated with Demodex infestation in blepharitis patients and the rates of eyelash Demodex colonization among blepharitic patients and healthy individuals in Thailand.Patients and Methods: This was a prospective, case–control clinical study. Eighty-three controls and 43 blepharitic patients were consecutively enrolled from Walailak University Hospital. Each patient answered a questionnaire, underwent a complete eye exam, and had four lashes from each eye epilated; eyelashes were directly examined under a light microscope. Ocular signs, including types of eyelash debris (waxy debris, scaly debris, or cylindrical dandruff (CD)), erythema and telangiectasia of the eyelid, were noted.Results: Demodex infestation was observed more frequently among patients with blepharitis than among controls (67.4% in the blepharitis group, 26.5% in the control group, p-value < 0.001). The participants with Demodex infestation were 5.7 times more likely to have blepharitis than the controls (odds ratio 5.74; 95% confidence interval 2.57– 12.82, p-value < 0.001). Clinical signs that were significantly (p-value < 0.05) related to demodicosis were lid erythema, lid telangiectasia, and any type of eyelash debris (scaly, waxy, or CD).Conclusion: In contrast to previous studies that found only CD to be highly associated with eyelash demodicosis, we found multiple suggestive signs: any kind of debris on eyelashes (scaly, waxy, or CD), eyelid erythema, and eyelid telangiectasia. Approximately one-quarter (26.5%) of the studied population had asymptomatic mite colonization. Demodex infestation should therefore always be on the list of possible etiologies when treating patients with blepharitis or other ocular surface-related problems.Keywords: Demodex, blepharitis, eyelid signs, debris, Thailand |
| first_indexed | 2024-12-23T02:16:31Z |
| format | Article |
| id | doaj.art-902ad3f846da405d9a34dc4808b5bdb7 |
| institution | Directory Open Access Journal |
| issn | 1177-5483 |
| language | English |
| last_indexed | 2024-12-23T02:16:31Z |
| publishDate | 2021-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-902ad3f846da405d9a34dc4808b5bdb72022-12-21T18:03:40ZengDove Medical PressClinical Ophthalmology1177-54832021-02-01Volume 1567167862204Multiple Eyelid Signs are Suggestive of Demodex InfestationUdomwech LPhasuk NLunla Udomwech, Nonthapan Phasuk School of Medicine, Walailak University, Nakhon Si Thammarat, ThailandCorrespondence: Lunla UdomwechSchool of Medicine, Walailak University, 222 Thaiburi, Tha Sala, Nakhon Si Thammarat, 80160, ThailandTel +6675 672 801Fax +6675 672 807Email lunla.ud@wu.ac.thPurpose: To determine the signs associated with Demodex infestation in blepharitis patients and the rates of eyelash Demodex colonization among blepharitic patients and healthy individuals in Thailand.Patients and Methods: This was a prospective, case–control clinical study. Eighty-three controls and 43 blepharitic patients were consecutively enrolled from Walailak University Hospital. Each patient answered a questionnaire, underwent a complete eye exam, and had four lashes from each eye epilated; eyelashes were directly examined under a light microscope. Ocular signs, including types of eyelash debris (waxy debris, scaly debris, or cylindrical dandruff (CD)), erythema and telangiectasia of the eyelid, were noted.Results: Demodex infestation was observed more frequently among patients with blepharitis than among controls (67.4% in the blepharitis group, 26.5% in the control group, p-value < 0.001). The participants with Demodex infestation were 5.7 times more likely to have blepharitis than the controls (odds ratio 5.74; 95% confidence interval 2.57– 12.82, p-value < 0.001). Clinical signs that were significantly (p-value < 0.05) related to demodicosis were lid erythema, lid telangiectasia, and any type of eyelash debris (scaly, waxy, or CD).Conclusion: In contrast to previous studies that found only CD to be highly associated with eyelash demodicosis, we found multiple suggestive signs: any kind of debris on eyelashes (scaly, waxy, or CD), eyelid erythema, and eyelid telangiectasia. Approximately one-quarter (26.5%) of the studied population had asymptomatic mite colonization. Demodex infestation should therefore always be on the list of possible etiologies when treating patients with blepharitis or other ocular surface-related problems.Keywords: Demodex, blepharitis, eyelid signs, debris, Thailandhttps://www.dovepress.com/multiple-eyelid-signs-are-suggestive-of-demodex-infestation-peer-reviewed-article-OPTHdemodexblepharitiseyelid signsdebristhailand |
| spellingShingle | Udomwech L Phasuk N Multiple Eyelid Signs are Suggestive of Demodex Infestation Clinical Ophthalmology demodex blepharitis eyelid signs debris thailand |
| title | Multiple Eyelid Signs are Suggestive of Demodex Infestation |
| title_full | Multiple Eyelid Signs are Suggestive of Demodex Infestation |
| title_fullStr | Multiple Eyelid Signs are Suggestive of Demodex Infestation |
| title_full_unstemmed | Multiple Eyelid Signs are Suggestive of Demodex Infestation |
| title_short | Multiple Eyelid Signs are Suggestive of Demodex Infestation |
| title_sort | multiple eyelid signs are suggestive of demodex infestation |
| topic | demodex blepharitis eyelid signs debris thailand |
| url | https://www.dovepress.com/multiple-eyelid-signs-are-suggestive-of-demodex-infestation-peer-reviewed-article-OPTH |
| work_keys_str_mv | AT udomwechl multipleeyelidsignsaresuggestiveofdemodexinfestation AT phasukn multipleeyelidsignsaresuggestiveofdemodexinfestation |