AMPLITUDO SENSORY NEURON ACTION POTENTIAL USING AS INSTALLATION OF POLINEUROPATI DIAGNOSIS

Background. Polyneuropathy is the pathologic changes and functional disturbances in the peripheral nervous system. These changes manifest as sign and symptoms such as numbness, burning, allodynia, atrophy, and lose of stimulation responses. Diagnosing polyneuropathy can use electrodiagnostic method...

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Main Authors: Billi Kinesya, Machlusil Husna, Shahdevi Nandar Kurniawan, Mochammad Ridwan
Format: Article
Language:English
Published: University of Brawijaya 2018-01-01
Series:Malang Neurology Journal
Subjects:
Online Access:http://mnj.ub.ac.id/index.php/mnj/article/view/276
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author Billi Kinesya
Machlusil Husna
Shahdevi Nandar Kurniawan
Mochammad Ridwan
author_facet Billi Kinesya
Machlusil Husna
Shahdevi Nandar Kurniawan
Mochammad Ridwan
author_sort Billi Kinesya
collection DOAJ
description Background. Polyneuropathy is the pathologic changes and functional disturbances in the peripheral nervous system. These changes manifest as sign and symptoms such as numbness, burning, allodynia, atrophy, and lose of stimulation responses. Diagnosing polyneuropathy can use electrodiagnostic method like electroneuromyography (ENMG). One of the most sensitive ENMG parameters for polyneuropathy is SNAP amplitude which can be measured at Sural Nerve. Objective. The goal of this study is to know whether SNAP amplitude can be used to diagnose polyneuropathy. Methods. The study design is diagnostic test in cross-sectional method. Results. Samples were taken from 108 ENMG medical records of Neurology Department Saiful Anwar General Hospital during the whole 2014. Two variables which are compared are polyneuropathy diagnosis and SNAP amplitude. Fisher test shows significant differences between the two with p = 0.04. Diagnostic test shows sensitivity 68.3%, spesifisity 80%, positive predictive value 97.1%, and negative predictive value 20.5%. Conclusion. There is a significant relationship between SNAP amplitude reduction with the diagnosis of polyneuropathy.
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spelling doaj.art-902b4ea32bd344a9b892cad6d533a7b22022-12-22T02:50:08ZengUniversity of BrawijayaMalang Neurology Journal2407-67242442-50012018-01-014171110.21776/ub.mnj.2018.004.01.2AMPLITUDO SENSORY NEURON ACTION POTENTIAL USING AS INSTALLATION OF POLINEUROPATI DIAGNOSISBilli Kinesya0Machlusil Husna1Shahdevi Nandar Kurniawan2Mochammad Ridwan3Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Brawijaya, Malang, IndonesiaLaboratorium Neurologi Fakultas Kedokteran Universitas Brawijaya, Malang, IndonesiaLaboratorium Neurologi Fakultas Kedokteran Universitas Brawijaya, Malang, IndonesiaLaboratorium Rehabilitasi Medik Fakultas Kedokteran Universitas Brawijaya, Malang, IndonesiaBackground. Polyneuropathy is the pathologic changes and functional disturbances in the peripheral nervous system. These changes manifest as sign and symptoms such as numbness, burning, allodynia, atrophy, and lose of stimulation responses. Diagnosing polyneuropathy can use electrodiagnostic method like electroneuromyography (ENMG). One of the most sensitive ENMG parameters for polyneuropathy is SNAP amplitude which can be measured at Sural Nerve. Objective. The goal of this study is to know whether SNAP amplitude can be used to diagnose polyneuropathy. Methods. The study design is diagnostic test in cross-sectional method. Results. Samples were taken from 108 ENMG medical records of Neurology Department Saiful Anwar General Hospital during the whole 2014. Two variables which are compared are polyneuropathy diagnosis and SNAP amplitude. Fisher test shows significant differences between the two with p = 0.04. Diagnostic test shows sensitivity 68.3%, spesifisity 80%, positive predictive value 97.1%, and negative predictive value 20.5%. Conclusion. There is a significant relationship between SNAP amplitude reduction with the diagnosis of polyneuropathy.http://mnj.ub.ac.id/index.php/mnj/article/view/276PolyneuropathyENMGSNAP amplitude
spellingShingle Billi Kinesya
Machlusil Husna
Shahdevi Nandar Kurniawan
Mochammad Ridwan
AMPLITUDO SENSORY NEURON ACTION POTENTIAL USING AS INSTALLATION OF POLINEUROPATI DIAGNOSIS
Malang Neurology Journal
Polyneuropathy
ENMG
SNAP amplitude
title AMPLITUDO SENSORY NEURON ACTION POTENTIAL USING AS INSTALLATION OF POLINEUROPATI DIAGNOSIS
title_full AMPLITUDO SENSORY NEURON ACTION POTENTIAL USING AS INSTALLATION OF POLINEUROPATI DIAGNOSIS
title_fullStr AMPLITUDO SENSORY NEURON ACTION POTENTIAL USING AS INSTALLATION OF POLINEUROPATI DIAGNOSIS
title_full_unstemmed AMPLITUDO SENSORY NEURON ACTION POTENTIAL USING AS INSTALLATION OF POLINEUROPATI DIAGNOSIS
title_short AMPLITUDO SENSORY NEURON ACTION POTENTIAL USING AS INSTALLATION OF POLINEUROPATI DIAGNOSIS
title_sort amplitudo sensory neuron action potential using as installation of polineuropati diagnosis
topic Polyneuropathy
ENMG
SNAP amplitude
url http://mnj.ub.ac.id/index.php/mnj/article/view/276
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