Ligands of Therapeutic Utility for the Liver X Receptors

Ligands of Therapeutic Utility for the Liver X Receptors

Liver X receptors (LXRs) have been increasingly recognized as a potential therapeutic target to treat pathological conditions ranging from vascular and metabolic diseases, neurological degeneration, to cancers that are driven by lipid metabolism. Amidst intensifying efforts to discover ligands that...

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Bibliographic Details
Main Authors: Rajesh Komati, Dominick Spadoni, Shilong Zheng, Jayalakshmi Sridhar, Kevin E. Riley, Guangdi Wang
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Molecules
Subjects:
liver X receptors
LXRα
LXRβ specific ligands
atherosclerosis
diabetes
Alzheimer’s disease
cancer
lipid metabolism
molecular modeling
interaction energy
Online Access:http://www.mdpi.com/1420-3049/22/1/88

Internet

http://www.mdpi.com/1420-3049/22/1/88

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