An Integrated ISFET Sensor Array

A monolithically integrated ISFET sensor array and interface circuit are described. A new high-density, low-power source-drain follower was developed for the sensor array. ISFETs were formed by depositing Au/Ti extended-gate electrodes on standard MOSFETs, then thin silicon nitride layers using cata...

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Main Author: Kazuo Nakazato
Format: Article
Language:English
Published: MDPI AG 2009-11-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/9/11/8831/
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author Kazuo Nakazato
author_facet Kazuo Nakazato
author_sort Kazuo Nakazato
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description A monolithically integrated ISFET sensor array and interface circuit are described. A new high-density, low-power source-drain follower was developed for the sensor array. ISFETs were formed by depositing Au/Ti extended-gate electrodes on standard MOSFETs, then thin silicon nitride layers using catalytic chemical vapor deposition and/or SU-8 protective layers were formed on the extended-gate electrodes. Applications for the array include: (1) pH detection by statistical distribution observing time and space fluctuations; (2) DNA detection using thiol-modified or silane-coupled oligonucleotides; (3) bio-image sensing by converting photons to electrons using Photosystem I of Thermosynechococcus elongatus, and sensing the converted electric charges by ISFETs.
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spelling doaj.art-902e8f7512154fb9bce2183e7520d7592022-12-22T02:18:28ZengMDPI AGSensors1424-82202009-11-019118831885110.3390/s91108831An Integrated ISFET Sensor ArrayKazuo NakazatoA monolithically integrated ISFET sensor array and interface circuit are described. A new high-density, low-power source-drain follower was developed for the sensor array. ISFETs were formed by depositing Au/Ti extended-gate electrodes on standard MOSFETs, then thin silicon nitride layers using catalytic chemical vapor deposition and/or SU-8 protective layers were formed on the extended-gate electrodes. Applications for the array include: (1) pH detection by statistical distribution observing time and space fluctuations; (2) DNA detection using thiol-modified or silane-coupled oligonucleotides; (3) bio-image sensing by converting photons to electrons using Photosystem I of Thermosynechococcus elongatus, and sensing the converted electric charges by ISFETs.http://www.mdpi.com/1424-8220/9/11/8831/ISFETbiosensor arraysource-drain followerCMOS biotechnology
spellingShingle Kazuo Nakazato
An Integrated ISFET Sensor Array
Sensors
ISFET
biosensor array
source-drain follower
CMOS biotechnology
title An Integrated ISFET Sensor Array
title_full An Integrated ISFET Sensor Array
title_fullStr An Integrated ISFET Sensor Array
title_full_unstemmed An Integrated ISFET Sensor Array
title_short An Integrated ISFET Sensor Array
title_sort integrated isfet sensor array
topic ISFET
biosensor array
source-drain follower
CMOS biotechnology
url http://www.mdpi.com/1424-8220/9/11/8831/
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