Vesicular Darier’s disease: a case report and review of the English literature of a rare disease variant
Darier’s disease is an autosomal dominant inherited skin disorder resulting from mutations in the ATP2A2 gene, which encodes SERCA2, an endoplasmic reticulum calcium ATPase. Darier’s disease classically manifests as confluent hyperkeratotic brown-to-red papules that manifest and follow a seborrheic...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2023-08-01
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| Series: | SAGE Open Medical Case Reports |
| Online Access: | https://doi.org/10.1177/2050313X231195467 |
| _version_ | 1797733487043674112 |
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| author | Ahmed Mourad Habib A Kurwa Richard M Haber |
| author_facet | Ahmed Mourad Habib A Kurwa Richard M Haber |
| author_sort | Ahmed Mourad |
| collection | DOAJ |
| description | Darier’s disease is an autosomal dominant inherited skin disorder resulting from mutations in the ATP2A2 gene, which encodes SERCA2, an endoplasmic reticulum calcium ATPase. Darier’s disease classically manifests as confluent hyperkeratotic brown-to-red papules that manifest and follow a seborrheic distribution, which include the chest, neck, trunk, and face. Vesicular Darier’s disease is a rare variant of the disorder where patients develop numerous vesicles and bullae concurrently or independent of the more typical lesions found in Darier’s disease. |
| first_indexed | 2024-03-12T12:28:50Z |
| format | Article |
| id | doaj.art-902efae6e2724007a6db44a444555548 |
| institution | Directory Open Access Journal |
| issn | 2050-313X |
| language | English |
| last_indexed | 2024-03-12T12:28:50Z |
| publishDate | 2023-08-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | SAGE Open Medical Case Reports |
| spelling | doaj.art-902efae6e2724007a6db44a4445555482023-08-29T17:42:31ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2023-08-011110.1177/2050313X231195467Vesicular Darier’s disease: a case report and review of the English literature of a rare disease variantAhmed MouradHabib A KurwaRichard M HaberDarier’s disease is an autosomal dominant inherited skin disorder resulting from mutations in the ATP2A2 gene, which encodes SERCA2, an endoplasmic reticulum calcium ATPase. Darier’s disease classically manifests as confluent hyperkeratotic brown-to-red papules that manifest and follow a seborrheic distribution, which include the chest, neck, trunk, and face. Vesicular Darier’s disease is a rare variant of the disorder where patients develop numerous vesicles and bullae concurrently or independent of the more typical lesions found in Darier’s disease.https://doi.org/10.1177/2050313X231195467 |
| spellingShingle | Ahmed Mourad Habib A Kurwa Richard M Haber Vesicular Darier’s disease: a case report and review of the English literature of a rare disease variant SAGE Open Medical Case Reports |
| title | Vesicular Darier’s disease: a case report and review of the English literature of a rare disease variant |
| title_full | Vesicular Darier’s disease: a case report and review of the English literature of a rare disease variant |
| title_fullStr | Vesicular Darier’s disease: a case report and review of the English literature of a rare disease variant |
| title_full_unstemmed | Vesicular Darier’s disease: a case report and review of the English literature of a rare disease variant |
| title_short | Vesicular Darier’s disease: a case report and review of the English literature of a rare disease variant |
| title_sort | vesicular darier s disease a case report and review of the english literature of a rare disease variant |
| url | https://doi.org/10.1177/2050313X231195467 |
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