Clinical use of positron emission tomography for radiotherapy planning – Medical physics considerations

PET/CT imaging plays an increasing role in radiotherapy treatment planning. The aim of this article was to identify the major use cases and technical as well as medical physics challenges during integration of these data into treatment planning. Dedicated aspects, such as (i) PET/CT-based radiothera...

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Main Author: Daniela Thorwarth
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Zeitschrift für Medizinische Physik
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0939388922000939
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author Daniela Thorwarth
author_facet Daniela Thorwarth
author_sort Daniela Thorwarth
collection DOAJ
description PET/CT imaging plays an increasing role in radiotherapy treatment planning. The aim of this article was to identify the major use cases and technical as well as medical physics challenges during integration of these data into treatment planning. Dedicated aspects, such as (i) PET/CT-based radiotherapy simulation, (ii) PET-based target volume delineation, (iii) functional avoidance to optimized organ-at-risk sparing and (iv) functionally adapted individualized radiotherapy are discussed in this article. Furthermore, medical physics aspects to be taken into account are summarized and presented in form of check-lists.
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spelling doaj.art-903219b4d15e4108ba7d1aa5af9424db2023-12-20T07:33:24ZengElsevierZeitschrift für Medizinische Physik0939-38892023-02-013311321Clinical use of positron emission tomography for radiotherapy planning – Medical physics considerationsDaniela Thorwarth0Address: Section for Biomedical Physics, Department of Radiation Oncology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany.; Section for Biomedical Physics, Department of Radiation Oncology, University of Tübingen, Tübingen, Germany; German Cancer Consortium (DKTK), partner site Tübingen; and German Cancer Research Center (DKFZ), Heidelberg, GermanyPET/CT imaging plays an increasing role in radiotherapy treatment planning. The aim of this article was to identify the major use cases and technical as well as medical physics challenges during integration of these data into treatment planning. Dedicated aspects, such as (i) PET/CT-based radiotherapy simulation, (ii) PET-based target volume delineation, (iii) functional avoidance to optimized organ-at-risk sparing and (iv) functionally adapted individualized radiotherapy are discussed in this article. Furthermore, medical physics aspects to be taken into account are summarized and presented in form of check-lists.http://www.sciencedirect.com/science/article/pii/S0939388922000939RadiotherapyTreatment planningPET-based contouringFunctionally adapted radiotherapyDose painting
spellingShingle Daniela Thorwarth
Clinical use of positron emission tomography for radiotherapy planning – Medical physics considerations
Zeitschrift für Medizinische Physik
Radiotherapy
Treatment planning
PET-based contouring
Functionally adapted radiotherapy
Dose painting
title Clinical use of positron emission tomography for radiotherapy planning – Medical physics considerations
title_full Clinical use of positron emission tomography for radiotherapy planning – Medical physics considerations
title_fullStr Clinical use of positron emission tomography for radiotherapy planning – Medical physics considerations
title_full_unstemmed Clinical use of positron emission tomography for radiotherapy planning – Medical physics considerations
title_short Clinical use of positron emission tomography for radiotherapy planning – Medical physics considerations
title_sort clinical use of positron emission tomography for radiotherapy planning medical physics considerations
topic Radiotherapy
Treatment planning
PET-based contouring
Functionally adapted radiotherapy
Dose painting
url http://www.sciencedirect.com/science/article/pii/S0939388922000939
work_keys_str_mv AT danielathorwarth clinicaluseofpositronemissiontomographyforradiotherapyplanningmedicalphysicsconsiderations