Racial differences in 5-year relative survival rates of cervical cancer by stage at diagnosis, between African American (black) and white women, living in the state of Alabama, USA
Abstract Background Our objective was to assess racial differences in the 5-year relative survival rates (RSRs) of Cervical Cancer (CerCancer) by stage at diagnosis, between Black and White women, living in Alabama, USA. Methods Data for 3484 Blacks and 21,059 Whites diagnosed with CerCancer were ex...
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| Format: | Article |
| Language: | English |
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BMC
2020-09-01
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| Series: | BMC Cancer |
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| Online Access: | http://link.springer.com/article/10.1186/s12885-020-07338-7 |
| _version_ | 1818854522996391936 |
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| author | Ehsan Abdalla Roberta Troy Souleymane Fall Isra Elhussin Oyoyo Egiebor-Aiwan David Nganwa |
| author_facet | Ehsan Abdalla Roberta Troy Souleymane Fall Isra Elhussin Oyoyo Egiebor-Aiwan David Nganwa |
| author_sort | Ehsan Abdalla |
| collection | DOAJ |
| description | Abstract Background Our objective was to assess racial differences in the 5-year relative survival rates (RSRs) of Cervical Cancer (CerCancer) by stage at diagnosis, between Black and White women, living in Alabama, USA. Methods Data for 3484 Blacks and 21,059 Whites diagnosed with CerCancer were extracted from the 2004 to 2013 Surveillance, Epidemiology, and End Results (SEER) database. We incorporated age groups, CerCancer stages, county, and year of diagnosis to compare the RSR between Blacks and Whites, using SEER*Stat software. Results In urban, Black Belt (BB) and other rural counties, Whites diagnosed with localized stage of CerCancer always had better chances of survival because their RSRs were always more than 77%, compared to Blacks. Only exception was in Blacks living in other rural counties, who had a significantly higher RSR of 83.8% (95% Cl, 74.2–90.1). Which was the same as in Whites (83.8% (95% CI 74.5–89.9) living in BBC. Although, in other rural counties, Whites had a slightly lower RSR of 83.7% (95% CI 79.9–86.8%), their RSR was better compared to Blacks and Whites living in BB and other rural counties who had slightly higher RSRs of 83.8%. This was due to statistical precision, which depended on their larger sample size and a lower variability therefore, more reliability resulting in a tighter confidence interval with a smaller margin of error. In all the three county groups, Whites 15–44 years old diagnosed with localized stage of CerCancer had a higher RSR of 93.6% (95% CI 91.4–95.2%) for those living in urban and BB counties, and 94.6% (95% CI 93.6–95.4) for those living in other rural counties. The only exception was in Blacks 65–74 years old living in other rural counties who had the highest RSR of 96.9% (95% Cl, 82.9–99.5). However, Whites were considered to have a better RSR. This was also due to the statistical precision as mentioned above. Conclusion There were significant racial differences in the RSRs of CerCancer. Overall, Black women experienced the worst RSRs compared to their White counterparts. |
| first_indexed | 2024-12-19T07:54:03Z |
| format | Article |
| id | doaj.art-9034f1467f1d4aa7912a5376503d0450 |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-12-19T07:54:03Z |
| publishDate | 2020-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-9034f1467f1d4aa7912a5376503d04502022-12-21T20:30:03ZengBMCBMC Cancer1471-24072020-09-0120111210.1186/s12885-020-07338-7Racial differences in 5-year relative survival rates of cervical cancer by stage at diagnosis, between African American (black) and white women, living in the state of Alabama, USAEhsan Abdalla0Roberta Troy1Souleymane Fall2Isra Elhussin3Oyoyo Egiebor-Aiwan4David Nganwa5Department of Graduate Public Health (College of Veterinary Medicine), Tuskegee UniversityBiology Department (College of Arts and Sciences), Tuskegee UniversityDepartment of Agriculture and Environmental Sciences (College of Agriculture, Environment and Nutrition Sciences), Tuskegee UniversityIntegrative Biosciences PhD program, Tuskegee UniversitySouthern Illinois School of MedicineDepartment of Pathobiology/Department of Graduate Public Health, Tuskegee UniversityAbstract Background Our objective was to assess racial differences in the 5-year relative survival rates (RSRs) of Cervical Cancer (CerCancer) by stage at diagnosis, between Black and White women, living in Alabama, USA. Methods Data for 3484 Blacks and 21,059 Whites diagnosed with CerCancer were extracted from the 2004 to 2013 Surveillance, Epidemiology, and End Results (SEER) database. We incorporated age groups, CerCancer stages, county, and year of diagnosis to compare the RSR between Blacks and Whites, using SEER*Stat software. Results In urban, Black Belt (BB) and other rural counties, Whites diagnosed with localized stage of CerCancer always had better chances of survival because their RSRs were always more than 77%, compared to Blacks. Only exception was in Blacks living in other rural counties, who had a significantly higher RSR of 83.8% (95% Cl, 74.2–90.1). Which was the same as in Whites (83.8% (95% CI 74.5–89.9) living in BBC. Although, in other rural counties, Whites had a slightly lower RSR of 83.7% (95% CI 79.9–86.8%), their RSR was better compared to Blacks and Whites living in BB and other rural counties who had slightly higher RSRs of 83.8%. This was due to statistical precision, which depended on their larger sample size and a lower variability therefore, more reliability resulting in a tighter confidence interval with a smaller margin of error. In all the three county groups, Whites 15–44 years old diagnosed with localized stage of CerCancer had a higher RSR of 93.6% (95% CI 91.4–95.2%) for those living in urban and BB counties, and 94.6% (95% CI 93.6–95.4) for those living in other rural counties. The only exception was in Blacks 65–74 years old living in other rural counties who had the highest RSR of 96.9% (95% Cl, 82.9–99.5). However, Whites were considered to have a better RSR. This was also due to the statistical precision as mentioned above. Conclusion There were significant racial differences in the RSRs of CerCancer. Overall, Black women experienced the worst RSRs compared to their White counterparts.http://link.springer.com/article/10.1186/s12885-020-07338-7Cervical cancer5-year relative survival ratios (RSRs)UrbanBlack Belt and other rural counties of Alabama |
| spellingShingle | Ehsan Abdalla Roberta Troy Souleymane Fall Isra Elhussin Oyoyo Egiebor-Aiwan David Nganwa Racial differences in 5-year relative survival rates of cervical cancer by stage at diagnosis, between African American (black) and white women, living in the state of Alabama, USA BMC Cancer Cervical cancer 5-year relative survival ratios (RSRs) Urban Black Belt and other rural counties of Alabama |
| title | Racial differences in 5-year relative survival rates of cervical cancer by stage at diagnosis, between African American (black) and white women, living in the state of Alabama, USA |
| title_full | Racial differences in 5-year relative survival rates of cervical cancer by stage at diagnosis, between African American (black) and white women, living in the state of Alabama, USA |
| title_fullStr | Racial differences in 5-year relative survival rates of cervical cancer by stage at diagnosis, between African American (black) and white women, living in the state of Alabama, USA |
| title_full_unstemmed | Racial differences in 5-year relative survival rates of cervical cancer by stage at diagnosis, between African American (black) and white women, living in the state of Alabama, USA |
| title_short | Racial differences in 5-year relative survival rates of cervical cancer by stage at diagnosis, between African American (black) and white women, living in the state of Alabama, USA |
| title_sort | racial differences in 5 year relative survival rates of cervical cancer by stage at diagnosis between african american black and white women living in the state of alabama usa |
| topic | Cervical cancer 5-year relative survival ratios (RSRs) Urban Black Belt and other rural counties of Alabama |
| url | http://link.springer.com/article/10.1186/s12885-020-07338-7 |
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