Relapse of Pleomorphic Adenoma from Childhood to Adulthood: Case Report
Pleomorphic adenoma is rarely seen in childhood. After detailed literature search, we did not come across a case of frequent relapse of this benign tumor from childhood to adulthood. The World Health Organization defines relapse of pleomorphic adenoma as a histologically benign tumor that can have l...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2017-01-01
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| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/288262 |
| _version_ | 1797207689664659456 |
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| author | Stjepan Grabovac Đurđica Đurđica Grabovac Zrinka Puharić Vesna Malčić Dalipi |
| author_facet | Stjepan Grabovac Đurđica Đurđica Grabovac Zrinka Puharić Vesna Malčić Dalipi |
| author_sort | Stjepan Grabovac |
| collection | DOAJ |
| description | Pleomorphic adenoma is rarely seen in childhood. After detailed literature search, we did not come across a case of frequent relapse of this benign tumor from childhood to adulthood. The World Health Organization defines relapse of pleomorphic adenoma as a histologically benign tumor that can have local or distant metastasis. There is one hypothesis how benign tumor can metastasize. According to this hypothesis, probably during the first operative procedure the tissue around the tumor becomes permeable for tumor cells, which can lead to implantation of tumor cells into the surrounding tissue. In this case report, we present a case of a 30-year-old woman with pleomorphic adenoma of the submandibular gland, which relapsed three times. The patient was first operated on in 1993, at the age of 7 years. The first two relapses occurred in 1998 and 2001, at the age of 12 and 15, respectively. The last relapse occurred in 2015, at the age of 29 years. All relapses were localized in the submandibular region on the right side of the neck, where the primary tumor had been operated on. |
| first_indexed | 2024-04-24T09:26:54Z |
| format | Article |
| id | doaj.art-903585d6566d4733a0c49aa68c80dae5 |
| institution | Directory Open Access Journal |
| issn | 0353-9466 1333-9451 |
| language | English |
| last_indexed | 2024-04-24T09:26:54Z |
| publishDate | 2017-01-01 |
| publisher | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
| record_format | Article |
| series | Acta Clinica Croatica |
| spelling | doaj.art-903585d6566d4733a0c49aa68c80dae52024-04-15T14:40:25ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512017-01-0156.4.81281610.20471/acc.2017.56.04.33Relapse of Pleomorphic Adenoma from Childhood to Adulthood: Case ReportStjepan Grabovac0Đurđica Đurđica Grabovac1Zrinka Puharić2Vesna Malčić Dalipi3Bjelovar General Hospital, Department of Otorhinolaryngology, Bjelovar, CroatiaHigh Nursing College, Bjelovar High Technical School, Bjelovar, CroatiaHigh Nursing College, Bjelovar High Technical School, Bjelovar, CroatiaBjelovar General Hospital, Department of Otorhinolaryngology, Bjelovar, CroatiaPleomorphic adenoma is rarely seen in childhood. After detailed literature search, we did not come across a case of frequent relapse of this benign tumor from childhood to adulthood. The World Health Organization defines relapse of pleomorphic adenoma as a histologically benign tumor that can have local or distant metastasis. There is one hypothesis how benign tumor can metastasize. According to this hypothesis, probably during the first operative procedure the tissue around the tumor becomes permeable for tumor cells, which can lead to implantation of tumor cells into the surrounding tissue. In this case report, we present a case of a 30-year-old woman with pleomorphic adenoma of the submandibular gland, which relapsed three times. The patient was first operated on in 1993, at the age of 7 years. The first two relapses occurred in 1998 and 2001, at the age of 12 and 15, respectively. The last relapse occurred in 2015, at the age of 29 years. All relapses were localized in the submandibular region on the right side of the neck, where the primary tumor had been operated on.https://hrcak.srce.hr/file/288262Adenoma, pleomorphicSubmandibular glandNeoplasm recurrence, local |
| spellingShingle | Stjepan Grabovac Đurđica Đurđica Grabovac Zrinka Puharić Vesna Malčić Dalipi Relapse of Pleomorphic Adenoma from Childhood to Adulthood: Case Report Acta Clinica Croatica Adenoma, pleomorphic Submandibular gland Neoplasm recurrence, local |
| title | Relapse of Pleomorphic Adenoma from Childhood to Adulthood: Case Report |
| title_full | Relapse of Pleomorphic Adenoma from Childhood to Adulthood: Case Report |
| title_fullStr | Relapse of Pleomorphic Adenoma from Childhood to Adulthood: Case Report |
| title_full_unstemmed | Relapse of Pleomorphic Adenoma from Childhood to Adulthood: Case Report |
| title_short | Relapse of Pleomorphic Adenoma from Childhood to Adulthood: Case Report |
| title_sort | relapse of pleomorphic adenoma from childhood to adulthood case report |
| topic | Adenoma, pleomorphic Submandibular gland Neoplasm recurrence, local |
| url | https://hrcak.srce.hr/file/288262 |
| work_keys_str_mv | AT stjepangrabovac relapseofpleomorphicadenomafromchildhoodtoadulthoodcasereport AT đurđicađurđicagrabovac relapseofpleomorphicadenomafromchildhoodtoadulthoodcasereport AT zrinkapuharic relapseofpleomorphicadenomafromchildhoodtoadulthoodcasereport AT vesnamalcicdalipi relapseofpleomorphicadenomafromchildhoodtoadulthoodcasereport |