IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA
Background: Condylomata Acuminata (CA) is a sexually transmitted disease caused by the Human Papilloma Virus (HPV) type-specific and may be simultaneously co-infected with other HPV types associated with malignancy. Purpose: To differentiate between CA and histopathological of malignancy by i...
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Format: | Article |
Language: | English |
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Universitas Nahdlatul Ulama Surabaya
2019-02-01
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Series: | Medical and Health Science Journal |
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Online Access: | https://journal2.unusa.ac.id/index.php/MHSJ/article/view/926 |
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author | Meidyta Sinantryana Widyaswari Hans Lumintang Troef Soemarno |
author_facet | Meidyta Sinantryana Widyaswari Hans Lumintang Troef Soemarno |
author_sort | Meidyta Sinantryana Widyaswari |
collection | DOAJ |
description |
Background: Condylomata Acuminata (CA) is a sexually transmitted disease caused by the Human Papilloma Virus (HPV) type-specific and may be simultaneously co-infected with other HPV types associated with malignancy. Purpose: To differentiate between CA and histopathological of malignancy by immunohistochemistry. LiteratureReview: CA refers to benign epidermal proliferation caused by the HPV types 6 and 11, but co-infection with high- risk HPV types are common. The clinical presentation of CA can’t differentiate between benign or preneoplastik diplasia lesions. Koilocytes considered pathognomonic for HPV lesions, these findings sometimes don’t appear on CA, and histopathology was not accurate, that immunohistochemistry with MIB-1 (Ki-67) and p16 can beused. Conclusion: Immunohistochemistry examination can help differentiate the diagnosis between malignancy or non- malignancy in the case of CA.
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first_indexed | 2024-12-10T23:34:46Z |
format | Article |
id | doaj.art-903acd605b824a7a990eacbd6d86a03c |
institution | Directory Open Access Journal |
issn | 2549-7588 2549-7596 |
language | English |
last_indexed | 2024-12-10T23:34:46Z |
publishDate | 2019-02-01 |
publisher | Universitas Nahdlatul Ulama Surabaya |
record_format | Article |
series | Medical and Health Science Journal |
spelling | doaj.art-903acd605b824a7a990eacbd6d86a03c2022-12-22T01:29:13ZengUniversitas Nahdlatul Ulama SurabayaMedical and Health Science Journal2549-75882549-75962019-02-013110.33086/mhsj.v3i1.926IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATAMeidyta Sinantryana Widyaswari0Hans Lumintang1Troef Soemarno2Universitas Nahdlatul Ulama SurabayaUniversitas Nahdlatul Ulama SurabayaUniversitas Airlangga Background: Condylomata Acuminata (CA) is a sexually transmitted disease caused by the Human Papilloma Virus (HPV) type-specific and may be simultaneously co-infected with other HPV types associated with malignancy. Purpose: To differentiate between CA and histopathological of malignancy by immunohistochemistry. LiteratureReview: CA refers to benign epidermal proliferation caused by the HPV types 6 and 11, but co-infection with high- risk HPV types are common. The clinical presentation of CA can’t differentiate between benign or preneoplastik diplasia lesions. Koilocytes considered pathognomonic for HPV lesions, these findings sometimes don’t appear on CA, and histopathology was not accurate, that immunohistochemistry with MIB-1 (Ki-67) and p16 can beused. Conclusion: Immunohistochemistry examination can help differentiate the diagnosis between malignancy or non- malignancy in the case of CA. https://journal2.unusa.ac.id/index.php/MHSJ/article/view/926Condylomata AcuminatamalignancyimmunohistochemistryMIB-1(Ki-67)p16 |
spellingShingle | Meidyta Sinantryana Widyaswari Hans Lumintang Troef Soemarno IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA Medical and Health Science Journal Condylomata Acuminata malignancy immunohistochemistry MIB-1(Ki-67) p16 |
title | IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA |
title_full | IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA |
title_fullStr | IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA |
title_full_unstemmed | IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA |
title_short | IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA |
title_sort | imunohistokimia pada kondilomata akuminata |
topic | Condylomata Acuminata malignancy immunohistochemistry MIB-1(Ki-67) p16 |
url | https://journal2.unusa.ac.id/index.php/MHSJ/article/view/926 |
work_keys_str_mv | AT meidytasinantryanawidyaswari imunohistokimiapadakondilomataakuminata AT hanslumintang imunohistokimiapadakondilomataakuminata AT troefsoemarno imunohistokimiapadakondilomataakuminata |