IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA

Background: Condylomata Acuminata (CA) is a sexually transmitted disease caused by the Human Papilloma Virus (HPV) type-specific and may be simultaneously co-infected with other HPV types associated with malignancy. Purpose: To differentiate between CA and histopathological of malignancy by i...

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Main Authors: Meidyta Sinantryana Widyaswari, Hans Lumintang, Troef Soemarno
Format: Article
Language:English
Published: Universitas Nahdlatul Ulama Surabaya 2019-02-01
Series:Medical and Health Science Journal
Subjects:
Online Access:https://journal2.unusa.ac.id/index.php/MHSJ/article/view/926
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author Meidyta Sinantryana Widyaswari
Hans Lumintang
Troef Soemarno
author_facet Meidyta Sinantryana Widyaswari
Hans Lumintang
Troef Soemarno
author_sort Meidyta Sinantryana Widyaswari
collection DOAJ
description Background: Condylomata Acuminata (CA) is a sexually transmitted disease caused by the Human Papilloma Virus (HPV) type-specific and may be simultaneously co-infected with other HPV types associated with malignancy. Purpose: To differentiate between CA and histopathological of malignancy by immunohistochemistry. LiteratureReview: CA refers to benign epidermal proliferation caused by the HPV types 6 and 11, but co-infection with high- risk HPV types are common. The clinical presentation of CA can’t differentiate between benign or preneoplastik diplasia lesions. Koilocytes considered pathognomonic for HPV lesions, these findings sometimes don’t appear on CA, and histopathology was not accurate, that immunohistochemistry with MIB-1 (Ki-67) and p16 can beused. Conclusion: Immunohistochemistry examination can help differentiate the diagnosis between malignancy or non- malignancy in the case of CA.
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spelling doaj.art-903acd605b824a7a990eacbd6d86a03c2022-12-22T01:29:13ZengUniversitas Nahdlatul Ulama SurabayaMedical and Health Science Journal2549-75882549-75962019-02-013110.33086/mhsj.v3i1.926IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATAMeidyta Sinantryana Widyaswari0Hans Lumintang1Troef Soemarno2Universitas Nahdlatul Ulama SurabayaUniversitas Nahdlatul Ulama SurabayaUniversitas Airlangga Background: Condylomata Acuminata (CA) is a sexually transmitted disease caused by the Human Papilloma Virus (HPV) type-specific and may be simultaneously co-infected with other HPV types associated with malignancy. Purpose: To differentiate between CA and histopathological of malignancy by immunohistochemistry. LiteratureReview: CA refers to benign epidermal proliferation caused by the HPV types 6 and 11, but co-infection with high- risk HPV types are common. The clinical presentation of CA can’t differentiate between benign or preneoplastik diplasia lesions. Koilocytes considered pathognomonic for HPV lesions, these findings sometimes don’t appear on CA, and histopathology was not accurate, that immunohistochemistry with MIB-1 (Ki-67) and p16 can beused. Conclusion: Immunohistochemistry examination can help differentiate the diagnosis between malignancy or non- malignancy in the case of CA. https://journal2.unusa.ac.id/index.php/MHSJ/article/view/926Condylomata AcuminatamalignancyimmunohistochemistryMIB-1(Ki-67)p16
spellingShingle Meidyta Sinantryana Widyaswari
Hans Lumintang
Troef Soemarno
IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA
Medical and Health Science Journal
Condylomata Acuminata
malignancy
immunohistochemistry
MIB-1(Ki-67)
p16
title IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA
title_full IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA
title_fullStr IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA
title_full_unstemmed IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA
title_short IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA
title_sort imunohistokimia pada kondilomata akuminata
topic Condylomata Acuminata
malignancy
immunohistochemistry
MIB-1(Ki-67)
p16
url https://journal2.unusa.ac.id/index.php/MHSJ/article/view/926
work_keys_str_mv AT meidytasinantryanawidyaswari imunohistokimiapadakondilomataakuminata
AT hanslumintang imunohistokimiapadakondilomataakuminata
AT troefsoemarno imunohistokimiapadakondilomataakuminata