Histological examination of the palatine tonsils in chronic tonsillitis
The article is devoted to the problem of chronic tonsillitis. The aim of the study was to assess changes in the morphofunctional state of the palatine tonsils in chronic inflammation. The study presents comparative data of immunohistochemical examination of the tonsils in normal and chronic tonsilla...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Remedium Group LLC
2019-11-01
|
| Series: | Медицинский совет |
| Subjects: | |
| Online Access: | https://www.med-sovet.pro/jour/article/view/4420 |
| _version_ | 1797842183634550784 |
|---|---|
| author | V. T. Pal’chun A. V. Gurov T. K. Dubovaya A. G. Ermolaev |
| author_facet | V. T. Pal’chun A. V. Gurov T. K. Dubovaya A. G. Ermolaev |
| author_sort | V. T. Pal’chun |
| collection | DOAJ |
| description | The article is devoted to the problem of chronic tonsillitis. The aim of the study was to assess changes in the morphofunctional state of the palatine tonsils in chronic inflammation. The study presents comparative data of immunohistochemical examination of the tonsils in normal and chronic tonsillar pathology. The authors used the clinical classification of chronic tonsillitis developed by B.S. Preobrazhensky and V.T. Pal’chun. Histological changes in the palatine tonsils of patients with toxic-allergic form 2 chronic tonsillitis were described in accordance with this classification. The control group represented palatine tonsils tissue taken from patients without chronic tonsillitis. The examination was carried out using markers of apoptosis, antiapoptosis, cell proliferation, as well as various types of lymphocytes. The authors describe a tonsil tissue handling technique, morphological and functional state in each study group, compared the studied parameters in two groups, reflected the dynamics of changes in the palatine tonsils with chronic tonsillitis. Increased apoptotic and anti-apoptotic activity combined with decreased cell proliferation, increased number of T-helpers and B-lymphocytes gives evidence of significantly decreased functional activity of the palatine tonsils in chronic inflammation. These changes are correlated with the clinical picture to develop the most optimal management of the disease. |
| first_indexed | 2024-04-09T16:43:41Z |
| format | Article |
| id | doaj.art-903b693f1937400ea43ae0a1faeb2246 |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:43:41Z |
| publishDate | 2019-11-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-903b693f1937400ea43ae0a1faeb22462023-04-23T06:56:35ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902019-11-01020687110.21518/2079-701X-2019-20-68-713969Histological examination of the palatine tonsils in chronic tonsillitisV. T. Pal’chun0A. V. Gurov1T. K. Dubovaya2A. G. Ermolaev3Pirogov Russian National Research Medical UniversityPirogov Russian National Research Medical UniversityPirogov Russian National Research Medical UniversityPirogov Russian National Research Medical UniversityThe article is devoted to the problem of chronic tonsillitis. The aim of the study was to assess changes in the morphofunctional state of the palatine tonsils in chronic inflammation. The study presents comparative data of immunohistochemical examination of the tonsils in normal and chronic tonsillar pathology. The authors used the clinical classification of chronic tonsillitis developed by B.S. Preobrazhensky and V.T. Pal’chun. Histological changes in the palatine tonsils of patients with toxic-allergic form 2 chronic tonsillitis were described in accordance with this classification. The control group represented palatine tonsils tissue taken from patients without chronic tonsillitis. The examination was carried out using markers of apoptosis, antiapoptosis, cell proliferation, as well as various types of lymphocytes. The authors describe a tonsil tissue handling technique, morphological and functional state in each study group, compared the studied parameters in two groups, reflected the dynamics of changes in the palatine tonsils with chronic tonsillitis. Increased apoptotic and anti-apoptotic activity combined with decreased cell proliferation, increased number of T-helpers and B-lymphocytes gives evidence of significantly decreased functional activity of the palatine tonsils in chronic inflammation. These changes are correlated with the clinical picture to develop the most optimal management of the disease.https://www.med-sovet.pro/jour/article/view/4420chronic tonsillitisimmunohistochemistryproliferationapoptosisantiapoptosist-lymphocytesb-lymphocytes |
| spellingShingle | V. T. Pal’chun A. V. Gurov T. K. Dubovaya A. G. Ermolaev Histological examination of the palatine tonsils in chronic tonsillitis Медицинский совет chronic tonsillitis immunohistochemistry proliferation apoptosis antiapoptosis t-lymphocytes b-lymphocytes |
| title | Histological examination of the palatine tonsils in chronic tonsillitis |
| title_full | Histological examination of the palatine tonsils in chronic tonsillitis |
| title_fullStr | Histological examination of the palatine tonsils in chronic tonsillitis |
| title_full_unstemmed | Histological examination of the palatine tonsils in chronic tonsillitis |
| title_short | Histological examination of the palatine tonsils in chronic tonsillitis |
| title_sort | histological examination of the palatine tonsils in chronic tonsillitis |
| topic | chronic tonsillitis immunohistochemistry proliferation apoptosis antiapoptosis t-lymphocytes b-lymphocytes |
| url | https://www.med-sovet.pro/jour/article/view/4420 |
| work_keys_str_mv | AT vtpalchun histologicalexaminationofthepalatinetonsilsinchronictonsillitis AT avgurov histologicalexaminationofthepalatinetonsilsinchronictonsillitis AT tkdubovaya histologicalexaminationofthepalatinetonsilsinchronictonsillitis AT agermolaev histologicalexaminationofthepalatinetonsilsinchronictonsillitis |