Evaluation of Acute and Sub-Acute Toxicity, Oxidative Stress and Molecular Docking of Two Nitrofuranyl Amides as Promising Anti-Tuberculosis Agents

Evaluation of Acute and Sub-Acute Toxicity, Oxidative Stress and Molecular Docking of Two Nitrofuranyl Amides as Promising Anti-Tuberculosis Agents

Tuberculosis (TB) remains a widespread infectious disease and one of the top 10 causes of death worldwide. Nevertheless, despite significant advances in the development of new drugs against tuberculosis, many therapies and preventive measures do not lead to the expected favorable health results for...

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Bibliographic Details
Main Authors: Simeon Dimitrov, Ivaylo Slavchev, Rumyana Simeonova, Milka Mileva, Tania Pencheva, Stanislav Philipov, Almira Georgieva, Elina Tsvetanova, Yoanna Teneva, Nadezhda Rimpova, Georgi Dobrikov, Violeta Valcheva
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biomolecules
Subjects:
nitrofuranyl amides
acute and sub-acute toxicity
markers of oxidative stress
molecular docking
pathomorphological evaluation
Online Access:https://www.mdpi.com/2218-273X/13/8/1174

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