Single-molecule RNA capture-assisted droplet digital loop-mediated isothermal amplification for ultrasensitive and rapid detection of infectious pathogens

Abstract To minimize and control the transmission of infectious diseases, a sensitive, accurate, rapid, and robust assay strategy for application on-site screening is critical. Here, we report single-molecule RNA capture-assisted digital RT-LAMP (SCADL) for point-of-care testing of infectious diseas...

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Bibliographic Details
Main Authors: Liying Jiang, Xianghao Lan, Linjiao Ren, Zhiyuan Jin, Xuchen Shan, Mingzhu Yang, Lingqian Chang
Format: Article
Language:English
Published: Nature Publishing Group 2023-09-01
Series:Microsystems & Nanoengineering
Online Access:https://doi.org/10.1038/s41378-023-00576-2