Analysis of the Phenotype of Mycobacterium tuberculosis-Specific CD4+ T Cells to Discriminate Latent from Active Tuberculosis in HIV-Uninfected and HIV-Infected Individuals
Several immune-based assays have been suggested to differentiate latent from active tuberculosis (TB). However, their relative performance as well as their efficacy in HIV-infected persons, a highly at-risk population, remains unclear. In a study of 81 individuals, divided into four groups based on...
Main Authors: | Catherine Riou, Natacha Berkowitz, Rene Goliath, Wendy A. Burgers, Robert J. Wilkinson |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-08-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fimmu.2017.00968/full |
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