Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review
Malignant mesothelioma is an infrequent tumor that initiates from the mesothelial cells lining of body cavities. The great majority of mesotheliomas originate in the pleural cavity, while the remaining cases initiate in the peritoneal cavity, in the pericardial cavity or on the tunica vaginalis. Usu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-03-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/21/5/1839 |
| _version_ | 1811223064675876864 |
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| author | Alfonso Baldi Antonio De Luca Patrizia Maiorano Costantino D’Angelo Antonio Giordano |
| author_facet | Alfonso Baldi Antonio De Luca Patrizia Maiorano Costantino D’Angelo Antonio Giordano |
| author_sort | Alfonso Baldi |
| collection | DOAJ |
| description | Malignant mesothelioma is an infrequent tumor that initiates from the mesothelial cells lining of body cavities. The great majority of mesotheliomas originate in the pleural cavity, while the remaining cases initiate in the peritoneal cavity, in the pericardial cavity or on the tunica vaginalis. Usually, mesotheliomas grow in a diffuse pattern and tend to enclose and compress the organs in the various body cavities. Mesothelioma incidence is increasing worldwide and still today, the prognosis is very poor, with a reported median survival of approximately one year from presentation. Thus, the development of alternative and more effective therapies is currently an urgent requirement. The aim of this review article was to describe recent findings about the anti-cancer activity of curcumin and some of its derivatives on mesotheliomas. The potential clinical implications of these findings are discussed. |
| first_indexed | 2024-04-12T08:25:29Z |
| format | Article |
| id | doaj.art-90463bc7da3448adb311e53fee207540 |
| institution | Directory Open Access Journal |
| issn | 1422-0067 |
| language | English |
| last_indexed | 2024-04-12T08:25:29Z |
| publishDate | 2020-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-90463bc7da3448adb311e53fee2075402022-12-22T03:40:23ZengMDPI AGInternational Journal of Molecular Sciences1422-00672020-03-01215183910.3390/ijms21051839ijms21051839Curcumin as an Anticancer Agent in Malignant Mesothelioma: A ReviewAlfonso Baldi0Antonio De Luca1Patrizia Maiorano2Costantino D’Angelo3Antonio Giordano4Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania “L. Vanvitelli”, 81100 Caserta, ItalyDepartment of Mental and Physical Health and Preventive Medicine, Section of Human Anatomy, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, ItalyDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, ItalyDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, ItalyMalignant mesothelioma is an infrequent tumor that initiates from the mesothelial cells lining of body cavities. The great majority of mesotheliomas originate in the pleural cavity, while the remaining cases initiate in the peritoneal cavity, in the pericardial cavity or on the tunica vaginalis. Usually, mesotheliomas grow in a diffuse pattern and tend to enclose and compress the organs in the various body cavities. Mesothelioma incidence is increasing worldwide and still today, the prognosis is very poor, with a reported median survival of approximately one year from presentation. Thus, the development of alternative and more effective therapies is currently an urgent requirement. The aim of this review article was to describe recent findings about the anti-cancer activity of curcumin and some of its derivatives on mesotheliomas. The potential clinical implications of these findings are discussed.https://www.mdpi.com/1422-0067/21/5/1839curcuminmesotheliomapiperinephytochemicaltherapy |
| spellingShingle | Alfonso Baldi Antonio De Luca Patrizia Maiorano Costantino D’Angelo Antonio Giordano Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review International Journal of Molecular Sciences curcumin mesothelioma piperine phytochemical therapy |
| title | Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review |
| title_full | Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review |
| title_fullStr | Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review |
| title_full_unstemmed | Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review |
| title_short | Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review |
| title_sort | curcumin as an anticancer agent in malignant mesothelioma a review |
| topic | curcumin mesothelioma piperine phytochemical therapy |
| url | https://www.mdpi.com/1422-0067/21/5/1839 |
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