Investigation of Toxoplasma Gondii, Rubella virus and Cytomegalovirus Infections in Pregnancy, Retrospective Evaluation of Avidity Tests and Perinatal Follow-up Results
Aim: In this study, it was aimed to investigate Toxoplasma Gondii, Rubella virus and Cytomegalovirus (CMV) IgM and IgG results, the avidity tests and perinatal follow-up results retrospectively. Material and Method: Test results of pregnant women who applied to Gynecology and Obstetrics Polyclinics...
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| Format: | Article |
| Language: | English |
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Rabia Yılmaz
2022-09-01
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| Series: | Journal of Contemporary Medicine |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/2465165 |
| _version_ | 1797860687776579584 |
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| author | Mehmet Keçecioğlu Tuğba Kula Atik Alev Çetin Duran Begüm Nalça Erdin |
| author_facet | Mehmet Keçecioğlu Tuğba Kula Atik Alev Çetin Duran Begüm Nalça Erdin |
| author_sort | Mehmet Keçecioğlu |
| collection | DOAJ |
| description | Aim: In this study, it was aimed to investigate Toxoplasma Gondii, Rubella virus and Cytomegalovirus (CMV) IgM and IgG results, the avidity tests and perinatal follow-up results retrospectively.
Material and Method: Test results of pregnant women who applied to Gynecology and Obstetrics Polyclinics in 2017-2018 were analyzed retrospectively.When IgM result was positive for any of these infections, IgG avidity indices, ultrasound (USG) findings, prenatal screening results, amniocentesis results, week of gestation that IgM positivity was observed, and if any treatments applied for these infections, were examined from the file records of pregnant women.
Results: It was observed that 24.1% of 6719 patients were Toxoplasma IgG, 98.9% were Rubella IgG and 98.7% were CMV IgG positive. When the IgM positivity was examined, it was seen that this rate was 0.46% (n=31) for Toxoplasma, 0.16% (n=11) for Rubella and 0.7% (n=47) for CMV. There was only 9 low avidity test results for Toxoplasma Gondii. But there was no evidence of perinatal infection associated with these infectious agents .
Conclusion: In conclusion, screening for toxoplasma, rubella and CMV infections during pregnancy is still a controversial subject and there is no national screening programme in Turkey. Knowing the seroprevalence is of great importance in establishing national screening strategies and providing consultancy to pregnant women about protection from these infections. From this point of view our study is valuable in that it contributes to these data as the first study conducted in Balıkesir region on this subject |
| first_indexed | 2024-04-09T21:50:52Z |
| format | Article |
| id | doaj.art-9047bc62a1474ccc96ceb69b827c69f1 |
| institution | Directory Open Access Journal |
| issn | 2667-7180 |
| language | English |
| last_indexed | 2024-04-09T21:50:52Z |
| publishDate | 2022-09-01 |
| publisher | Rabia Yılmaz |
| record_format | Article |
| series | Journal of Contemporary Medicine |
| spelling | doaj.art-9047bc62a1474ccc96ceb69b827c69f12023-03-24T19:43:22ZengRabia YılmazJournal of Contemporary Medicine2667-71802022-09-0112571672110.16899/jcm.11256941809Investigation of Toxoplasma Gondii, Rubella virus and Cytomegalovirus Infections in Pregnancy, Retrospective Evaluation of Avidity Tests and Perinatal Follow-up ResultsMehmet Keçecioğlu0Tuğba Kula Atik1Alev Çetin Duran2Begüm Nalça Erdin3Balıkesir City Hospital, Department of Obstetrics and Gynecology, Obstetrician and gynecologistBALIKESİR ÜNİVERSİTESİ, TIP FAKÜLTESİBalıkesir City Hospital, Microbiology-Basic Immunology Laboratory, Microbiology Specialist, Balıkesir, Turkeysağlık bilimleri üniversitesi ümraniye eğitim ve araştırma hastanesi mikrobiyolojiAim: In this study, it was aimed to investigate Toxoplasma Gondii, Rubella virus and Cytomegalovirus (CMV) IgM and IgG results, the avidity tests and perinatal follow-up results retrospectively. Material and Method: Test results of pregnant women who applied to Gynecology and Obstetrics Polyclinics in 2017-2018 were analyzed retrospectively.When IgM result was positive for any of these infections, IgG avidity indices, ultrasound (USG) findings, prenatal screening results, amniocentesis results, week of gestation that IgM positivity was observed, and if any treatments applied for these infections, were examined from the file records of pregnant women. Results: It was observed that 24.1% of 6719 patients were Toxoplasma IgG, 98.9% were Rubella IgG and 98.7% were CMV IgG positive. When the IgM positivity was examined, it was seen that this rate was 0.46% (n=31) for Toxoplasma, 0.16% (n=11) for Rubella and 0.7% (n=47) for CMV. There was only 9 low avidity test results for Toxoplasma Gondii. But there was no evidence of perinatal infection associated with these infectious agents . Conclusion: In conclusion, screening for toxoplasma, rubella and CMV infections during pregnancy is still a controversial subject and there is no national screening programme in Turkey. Knowing the seroprevalence is of great importance in establishing national screening strategies and providing consultancy to pregnant women about protection from these infections. From this point of view our study is valuable in that it contributes to these data as the first study conducted in Balıkesir region on this subjecthttps://dergipark.org.tr/tr/download/article-file/2465165torchcongenital infectionaviditytorchkonjenital infeksiyonavidite |
| spellingShingle | Mehmet Keçecioğlu Tuğba Kula Atik Alev Çetin Duran Begüm Nalça Erdin Investigation of Toxoplasma Gondii, Rubella virus and Cytomegalovirus Infections in Pregnancy, Retrospective Evaluation of Avidity Tests and Perinatal Follow-up Results Journal of Contemporary Medicine torch congenital infection avidity torch konjenital infeksiyon avidite |
| title | Investigation of Toxoplasma Gondii, Rubella virus and Cytomegalovirus Infections in Pregnancy, Retrospective Evaluation of Avidity Tests and Perinatal Follow-up Results |
| title_full | Investigation of Toxoplasma Gondii, Rubella virus and Cytomegalovirus Infections in Pregnancy, Retrospective Evaluation of Avidity Tests and Perinatal Follow-up Results |
| title_fullStr | Investigation of Toxoplasma Gondii, Rubella virus and Cytomegalovirus Infections in Pregnancy, Retrospective Evaluation of Avidity Tests and Perinatal Follow-up Results |
| title_full_unstemmed | Investigation of Toxoplasma Gondii, Rubella virus and Cytomegalovirus Infections in Pregnancy, Retrospective Evaluation of Avidity Tests and Perinatal Follow-up Results |
| title_short | Investigation of Toxoplasma Gondii, Rubella virus and Cytomegalovirus Infections in Pregnancy, Retrospective Evaluation of Avidity Tests and Perinatal Follow-up Results |
| title_sort | investigation of toxoplasma gondii rubella virus and cytomegalovirus infections in pregnancy retrospective evaluation of avidity tests and perinatal follow up results |
| topic | torch congenital infection avidity torch konjenital infeksiyon avidite |
| url | https://dergipark.org.tr/tr/download/article-file/2465165 |
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