Cervical Carcinoma: Oncobiology and Biomarkers
Cervical cancer is one of the most common types of carcinomas causing morbidity and mortality in women in all countries of the world. At the moment, the oncology, oncobiology, and oncomorphology of cervical cancer are characterized by the accumulation of new information; various molecular biological...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-11-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/22/22/12571 |
| _version_ | 1797509942435905536 |
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| author | Larisa V. Volkova Alexander I. Pashov Nadezhda N. Omelchuk |
| author_facet | Larisa V. Volkova Alexander I. Pashov Nadezhda N. Omelchuk |
| author_sort | Larisa V. Volkova |
| collection | DOAJ |
| description | Cervical cancer is one of the most common types of carcinomas causing morbidity and mortality in women in all countries of the world. At the moment, the oncology, oncobiology, and oncomorphology of cervical cancer are characterized by the accumulation of new information; various molecular biological, genetic, and immunohistochemical methods of investigation of the mechanisms of cervical carcinogenesis are tested and applied; targeted antitumour drugs and diagnostic, prognostic, and predictive biomarkers are being searched for. Many issues of the etiopathogenesis of cervical cancer have not been sufficiently studied, and the role of many biomarkers characterizing various stages of cervical carcinogenesis remains unclear. Therefore, the target of this review is to systematize and understand several problems in the pathogenesis of cervical cancer and to evaluate the significance and role of biomarkers in cervical carcinogenesis. |
| first_indexed | 2024-03-10T05:24:52Z |
| format | Article |
| id | doaj.art-9049e4a5cbf6405083b4b4d17931fa4d |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T05:24:52Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-9049e4a5cbf6405083b4b4d17931fa4d2023-11-22T23:44:26ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-11-0122221257110.3390/ijms222212571Cervical Carcinoma: Oncobiology and BiomarkersLarisa V. Volkova0Alexander I. Pashov1Nadezhda N. Omelchuk2Laboratory of Immunohistochemistry, Pathology and Clinical Diagnostics, Department of Fundamental Medicine, Medical Institute, Immanuel Kant Baltic Federal University, 236041 Kaliningrad, RussiaDepartment of Obstetrics and Gynecology, Medical Institute, Immanuel Kant Baltic Federal, 236041 Kaliningrad, RussiaDepartment of Clinical Laboratory Diagnostics, Faculty of Continuing Medical Education, People’s Friendship University, 117198 Moscow, RussiaCervical cancer is one of the most common types of carcinomas causing morbidity and mortality in women in all countries of the world. At the moment, the oncology, oncobiology, and oncomorphology of cervical cancer are characterized by the accumulation of new information; various molecular biological, genetic, and immunohistochemical methods of investigation of the mechanisms of cervical carcinogenesis are tested and applied; targeted antitumour drugs and diagnostic, prognostic, and predictive biomarkers are being searched for. Many issues of the etiopathogenesis of cervical cancer have not been sufficiently studied, and the role of many biomarkers characterizing various stages of cervical carcinogenesis remains unclear. Therefore, the target of this review is to systematize and understand several problems in the pathogenesis of cervical cancer and to evaluate the significance and role of biomarkers in cervical carcinogenesis.https://www.mdpi.com/1422-0067/22/22/12571carcinoma of the cervixcervical carcinogenesisbiomarkersimmunohistochemistry |
| spellingShingle | Larisa V. Volkova Alexander I. Pashov Nadezhda N. Omelchuk Cervical Carcinoma: Oncobiology and Biomarkers International Journal of Molecular Sciences carcinoma of the cervix cervical carcinogenesis biomarkers immunohistochemistry |
| title | Cervical Carcinoma: Oncobiology and Biomarkers |
| title_full | Cervical Carcinoma: Oncobiology and Biomarkers |
| title_fullStr | Cervical Carcinoma: Oncobiology and Biomarkers |
| title_full_unstemmed | Cervical Carcinoma: Oncobiology and Biomarkers |
| title_short | Cervical Carcinoma: Oncobiology and Biomarkers |
| title_sort | cervical carcinoma oncobiology and biomarkers |
| topic | carcinoma of the cervix cervical carcinogenesis biomarkers immunohistochemistry |
| url | https://www.mdpi.com/1422-0067/22/22/12571 |
| work_keys_str_mv | AT larisavvolkova cervicalcarcinomaoncobiologyandbiomarkers AT alexanderipashov cervicalcarcinomaoncobiologyandbiomarkers AT nadezhdanomelchuk cervicalcarcinomaoncobiologyandbiomarkers |