The Effect of Artificial Tears on Corneal Higher Order Aberrations in Dry Eye Patients

Purpose: To assess the effects of artificial tears on corneal higher order aberrations in dry eye patients. Materials and Methods: 30 right eyes of 30 newly diagnosed dry eye patients were evaluated in this prospective study. After routine ophthalmological examination, Schirmer test and tear break...

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Main Authors: Hasan Ali Bayhan, Seray Aslan Bayhan, İzzet Can
Format: Article
Language:English
Published: Galenos Yayinevi 2014-03-01
Series:Türk Oftalmoloji Dergisi
Subjects:
Online Access:http://www.oftalmoloji.org/article_2360/The-Effect-Of-Artificial-Tears-On-Corneal-Higher-Order-Aberrations-In-Dry-Eye-Patients
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author Hasan Ali Bayhan
Seray Aslan Bayhan
İzzet Can
author_facet Hasan Ali Bayhan
Seray Aslan Bayhan
İzzet Can
author_sort Hasan Ali Bayhan
collection DOAJ
description Purpose: To assess the effects of artificial tears on corneal higher order aberrations in dry eye patients. Materials and Methods: 30 right eyes of 30 newly diagnosed dry eye patients were evaluated in this prospective study. After routine ophthalmological examination, Schirmer test and tear break-up time (TBUT) test were performed in all patients. Anterior corneal aberrations were derived from conversion of the corneal elevation profile into corneal wavefront data with 6.0 mm pupil diameter using Zernike polynomails by corneal topography before and 5 minutes after instillation of artificial tear (Eyestil®). Corneal optical aberrations were compared before and after instillation of eyedrop. Results: The study included 17 women and 13 men; the average age of the patients was 44.36±13.22 years. Mean TBUT was 4.78±2.78 seconds and mean Schirmer value was 3.58±2.45 mm/5 minutes. After instillation of artificial tear, significant reductions in corneal total aberration from 1.120±0.35 µm to 0.960±0.34 µm, higher order aberration from 0.674±0.26 µm to 0.464±0.18 µm, coma-like aberration from 0.283±0.10 µm to 0.238±0.09 µm, and spherical-like aberration from 0.254±0.11 µm to 0.221±0.08 µm were detected (all, p<0.001). After eyedrop instillation, statistically significant increment was observed in Strehl ratio (p<0.001). Conclusion: As well as reducing the dry eye symptoms, artificial tears also cause increment in optical quality of the eye. Benefits of artificial tears on visual quality can be evaluated objectively via corneal wavefront aberrations. (Turk J Ophthalmol 2014; 44: 119-22)
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spelling doaj.art-904cd903264e4198a2ecafa3be2e79f82023-02-15T16:17:15ZengGalenos YayineviTürk Oftalmoloji Dergisi1300-06592147-26612014-03-0144211912210.4274/tjo.78557The Effect of Artificial Tears on Corneal Higher Order Aberrations in Dry Eye PatientsHasan Ali Bayhan0Seray Aslan Bayhan1İzzet Can2Bozok Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Yozgat, TürkiyeBozok Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Yozgat, TürkiyeÖzel Maya Göz Hastanesi, Ankara, TürkiyePurpose: To assess the effects of artificial tears on corneal higher order aberrations in dry eye patients. Materials and Methods: 30 right eyes of 30 newly diagnosed dry eye patients were evaluated in this prospective study. After routine ophthalmological examination, Schirmer test and tear break-up time (TBUT) test were performed in all patients. Anterior corneal aberrations were derived from conversion of the corneal elevation profile into corneal wavefront data with 6.0 mm pupil diameter using Zernike polynomails by corneal topography before and 5 minutes after instillation of artificial tear (Eyestil®). Corneal optical aberrations were compared before and after instillation of eyedrop. Results: The study included 17 women and 13 men; the average age of the patients was 44.36±13.22 years. Mean TBUT was 4.78±2.78 seconds and mean Schirmer value was 3.58±2.45 mm/5 minutes. After instillation of artificial tear, significant reductions in corneal total aberration from 1.120±0.35 µm to 0.960±0.34 µm, higher order aberration from 0.674±0.26 µm to 0.464±0.18 µm, coma-like aberration from 0.283±0.10 µm to 0.238±0.09 µm, and spherical-like aberration from 0.254±0.11 µm to 0.221±0.08 µm were detected (all, p<0.001). After eyedrop instillation, statistically significant increment was observed in Strehl ratio (p<0.001). Conclusion: As well as reducing the dry eye symptoms, artificial tears also cause increment in optical quality of the eye. Benefits of artificial tears on visual quality can be evaluated objectively via corneal wavefront aberrations. (Turk J Ophthalmol 2014; 44: 119-22)http://www.oftalmoloji.org/article_2360/The-Effect-Of-Artificial-Tears-On-Corneal-Higher-Order-Aberrations-In-Dry-Eye-PatientsDry eyecorneal topographycorneal aberrations
spellingShingle Hasan Ali Bayhan
Seray Aslan Bayhan
İzzet Can
The Effect of Artificial Tears on Corneal Higher Order Aberrations in Dry Eye Patients
Türk Oftalmoloji Dergisi
Dry eye
corneal topography
corneal aberrations
title The Effect of Artificial Tears on Corneal Higher Order Aberrations in Dry Eye Patients
title_full The Effect of Artificial Tears on Corneal Higher Order Aberrations in Dry Eye Patients
title_fullStr The Effect of Artificial Tears on Corneal Higher Order Aberrations in Dry Eye Patients
title_full_unstemmed The Effect of Artificial Tears on Corneal Higher Order Aberrations in Dry Eye Patients
title_short The Effect of Artificial Tears on Corneal Higher Order Aberrations in Dry Eye Patients
title_sort effect of artificial tears on corneal higher order aberrations in dry eye patients
topic Dry eye
corneal topography
corneal aberrations
url http://www.oftalmoloji.org/article_2360/The-Effect-Of-Artificial-Tears-On-Corneal-Higher-Order-Aberrations-In-Dry-Eye-Patients
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