Dandelion (<i>Taraxacum</i> Genus): A Review of Chemical Constituents and Pharmacological Effects
Dandelion (<i>Taraxacum</i> genus) is a perennial herb belonging to the Asteraceae family. As a well-known and extensively studied genus, dandelion comprises numerous species. Some species have been widely used in both complementary and alternative medicine to clear heat, detoxify, activ...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/13/5022 |
| _version_ | 1797591218487558144 |
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| author | Min Fan Xiao Zhang Huaping Song Yakong Zhang |
| author_facet | Min Fan Xiao Zhang Huaping Song Yakong Zhang |
| author_sort | Min Fan |
| collection | DOAJ |
| description | Dandelion (<i>Taraxacum</i> genus) is a perennial herb belonging to the Asteraceae family. As a well-known and extensively studied genus, dandelion comprises numerous species. Some species have been widely used in both complementary and alternative medicine to clear heat, detoxify, activate blood circulation, dispel stasis, and discharge urine. Multiple pharmacological studies have highlighted its therapeutic potential, including anti-bacterial, anti-oxidant, anti-cancer, and anti-rheumatic activities. Furthermore, bioactive compounds associated with these effects include sesquiterpenoids, phenolic compounds, essential oils, saccharides, flavonoids, sphingolipids, triterpenoids, sterols, coumarins, etc. Based on recent studies about the <i>Taraxacum</i> genus, the present review critically evaluates the current state of dandelion utilization and summarizes the significant roles of dandelion and its constituents in different diseases. We also focus on the reported phytology, chemical composition, pharmacology, and toxicity of dandelion, along with the main possible action mechanisms behind their therapeutic activities. Meanwhile, the challenges and future directions of the <i>Taraxacum</i> genus are also prospected in this review, thus highlighting its pharmaceutical research and practical clinical applications. |
| first_indexed | 2024-03-11T01:34:21Z |
| format | Article |
| id | doaj.art-90563576a80f483a9e0127129984468c |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T01:34:21Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-90563576a80f483a9e0127129984468c2023-11-18T17:07:02ZengMDPI AGMolecules1420-30492023-06-012813502210.3390/molecules28135022Dandelion (<i>Taraxacum</i> Genus): A Review of Chemical Constituents and Pharmacological EffectsMin Fan0Xiao Zhang1Huaping Song2Yakong Zhang3Department of Traditional Chinese Medicine, Gansu Medical College, Pingliang 744000, ChinaSanitation Test Center, Pingliang Center for Disease Control and Prevention, Pingliang 744000, ChinaDepartment of Traditional Chinese Medicine, Gansu Medical College, Pingliang 744000, ChinaSanitation Test Center, Pingliang Center for Disease Control and Prevention, Pingliang 744000, ChinaDandelion (<i>Taraxacum</i> genus) is a perennial herb belonging to the Asteraceae family. As a well-known and extensively studied genus, dandelion comprises numerous species. Some species have been widely used in both complementary and alternative medicine to clear heat, detoxify, activate blood circulation, dispel stasis, and discharge urine. Multiple pharmacological studies have highlighted its therapeutic potential, including anti-bacterial, anti-oxidant, anti-cancer, and anti-rheumatic activities. Furthermore, bioactive compounds associated with these effects include sesquiterpenoids, phenolic compounds, essential oils, saccharides, flavonoids, sphingolipids, triterpenoids, sterols, coumarins, etc. Based on recent studies about the <i>Taraxacum</i> genus, the present review critically evaluates the current state of dandelion utilization and summarizes the significant roles of dandelion and its constituents in different diseases. We also focus on the reported phytology, chemical composition, pharmacology, and toxicity of dandelion, along with the main possible action mechanisms behind their therapeutic activities. Meanwhile, the challenges and future directions of the <i>Taraxacum</i> genus are also prospected in this review, thus highlighting its pharmaceutical research and practical clinical applications.https://www.mdpi.com/1420-3049/28/13/5022<i>Taraxacum</i> genusdandelionphytologyplant active ingredientspharmacologytoxicity |
| spellingShingle | Min Fan Xiao Zhang Huaping Song Yakong Zhang Dandelion (<i>Taraxacum</i> Genus): A Review of Chemical Constituents and Pharmacological Effects Molecules <i>Taraxacum</i> genus dandelion phytology plant active ingredients pharmacology toxicity |
| title | Dandelion (<i>Taraxacum</i> Genus): A Review of Chemical Constituents and Pharmacological Effects |
| title_full | Dandelion (<i>Taraxacum</i> Genus): A Review of Chemical Constituents and Pharmacological Effects |
| title_fullStr | Dandelion (<i>Taraxacum</i> Genus): A Review of Chemical Constituents and Pharmacological Effects |
| title_full_unstemmed | Dandelion (<i>Taraxacum</i> Genus): A Review of Chemical Constituents and Pharmacological Effects |
| title_short | Dandelion (<i>Taraxacum</i> Genus): A Review of Chemical Constituents and Pharmacological Effects |
| title_sort | dandelion i taraxacum i genus a review of chemical constituents and pharmacological effects |
| topic | <i>Taraxacum</i> genus dandelion phytology plant active ingredients pharmacology toxicity |
| url | https://www.mdpi.com/1420-3049/28/13/5022 |
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