Severity of Coronary Artery Disease associated with Non-Alcoholic Fatty Liver

Background: Non-Alcoholic Fatty Liver Disease (NAFLD) is closely related to several metabolic disorders and is also associated with increased risk of cardiovascular disease (CVD), including coronary artery disease (CAD). Patients and methods: This was a prospective study involving patients who under...

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Main Authors: Albair Abdulmaseh*, Mohamed Elsenebsy, Hosam Ismael, Mohammed Tag-Adeen
Format: Article
Language:English
Published: South Valley University, Faculty of Medicine 2021-01-01
Series:SVU - International Journal of Medical Sciences
Subjects:
Online Access:https://svuijm.journals.ekb.eg/article_112039.html
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author Albair Abdulmaseh*
Mohamed Elsenebsy
Hosam Ismael
Mohammed Tag-Adeen
author_facet Albair Abdulmaseh*
Mohamed Elsenebsy
Hosam Ismael
Mohammed Tag-Adeen
author_sort Albair Abdulmaseh*
collection DOAJ
description Background: Non-Alcoholic Fatty Liver Disease (NAFLD) is closely related to several metabolic disorders and is also associated with increased risk of cardiovascular disease (CVD), including coronary artery disease (CAD). Patients and methods: This was a prospective study involving patients who underwent coronary catheterization and had proven coronary artery diseases.All patients were subjected to abdominal ultrasonography and transient elastography to detect NAFLD and grading of steatosis . Results: A total of 100 patient, with mean ageof 47.9 ± 8.4 years, 70% were males , 70% were diabetics. According to ultrasonographic findings, there were 58 patients (58%) normal and 42 patients (42%) with fatty liver. As regard degree of steatosis, there were 12 patients (12%) of S0, 38 patients (38%) of S1, 22 patients (22%) of S2 and 28 patients (28%) of S3.The mean of Genseni score was 50.9.There was highly statistical significant correlation (p-value < 0.001) between degree of steatosis and Genseni score in studied patients,the mean of Gensini score was 10.5, 21.7, 57.6 and 102.6 in Grade S0, S1, S2 and S3 respectively. Conclusion: The present study indicated a Statistically significant correlation between CAD and NAFLD.
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spelling doaj.art-905dc44510104a83bd4daa4b2b010d912022-12-21T21:23:30ZengSouth Valley University, Faculty of MedicineSVU - International Journal of Medical Sciences2735-427X2636-34022021-01-01416875https://dx.doi.org/10.21608/svuijm.2021.112039Severity of Coronary Artery Disease associated with Non-Alcoholic Fatty LiverAlbair Abdulmaseh*0 Mohamed Elsenebsy1 Hosam Ismael2 Mohammed Tag-Adeen3Internal Medicine Department, Qena Faculty of Medicine,South Valley UniversityInternal Medicine Department, Qena Faculty of Medicine,South Valley UniversityInternal Medicine Department, Qena Faculty of Medicine,South Valley UniversityInternal Medicine Department, Qena Faculty of Medicine,South Valley UniversityBackground: Non-Alcoholic Fatty Liver Disease (NAFLD) is closely related to several metabolic disorders and is also associated with increased risk of cardiovascular disease (CVD), including coronary artery disease (CAD). Patients and methods: This was a prospective study involving patients who underwent coronary catheterization and had proven coronary artery diseases.All patients were subjected to abdominal ultrasonography and transient elastography to detect NAFLD and grading of steatosis . Results: A total of 100 patient, with mean ageof 47.9 ± 8.4 years, 70% were males , 70% were diabetics. According to ultrasonographic findings, there were 58 patients (58%) normal and 42 patients (42%) with fatty liver. As regard degree of steatosis, there were 12 patients (12%) of S0, 38 patients (38%) of S1, 22 patients (22%) of S2 and 28 patients (28%) of S3.The mean of Genseni score was 50.9.There was highly statistical significant correlation (p-value < 0.001) between degree of steatosis and Genseni score in studied patients,the mean of Gensini score was 10.5, 21.7, 57.6 and 102.6 in Grade S0, S1, S2 and S3 respectively. Conclusion: The present study indicated a Statistically significant correlation between CAD and NAFLD.https://svuijm.journals.ekb.eg/article_112039.htmlnon-alcoholic fatty liver disease; coronary artery disease; gensini score
spellingShingle Albair Abdulmaseh*
Mohamed Elsenebsy
Hosam Ismael
Mohammed Tag-Adeen
Severity of Coronary Artery Disease associated with Non-Alcoholic Fatty Liver
SVU - International Journal of Medical Sciences
non-alcoholic fatty liver disease; coronary artery disease; gensini score
title Severity of Coronary Artery Disease associated with Non-Alcoholic Fatty Liver
title_full Severity of Coronary Artery Disease associated with Non-Alcoholic Fatty Liver
title_fullStr Severity of Coronary Artery Disease associated with Non-Alcoholic Fatty Liver
title_full_unstemmed Severity of Coronary Artery Disease associated with Non-Alcoholic Fatty Liver
title_short Severity of Coronary Artery Disease associated with Non-Alcoholic Fatty Liver
title_sort severity of coronary artery disease associated with non alcoholic fatty liver
topic non-alcoholic fatty liver disease; coronary artery disease; gensini score
url https://svuijm.journals.ekb.eg/article_112039.html
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AT hosamismael severityofcoronaryarterydiseaseassociatedwithnonalcoholicfattyliver
AT mohammedtagadeen severityofcoronaryarterydiseaseassociatedwithnonalcoholicfattyliver