Major biochemical constituents of Withania somnifera (ashwagandha) extract: A review of chemical analysis

Ashwagandha (Withania somnifera) is a very popular medicinal herb originated mainly in India and found in the Middle East and parts of Africa. Ashwagandha has gained recognition as the most revered plant in Ayurvedic medicine. Studies indicated that it is used as anxiolytic, anti-inflammatory, antio...

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Main Authors: Abdelwahed Mahmoud Tareq, Hegazy Maha A., Mohamed Ekram H.
Format: Article
Language:English
Published: De Gruyter 2023-03-01
Series:Reviews in Analytical Chemistry
Subjects:
Online Access:https://doi.org/10.1515/revac-2022-0055
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author Abdelwahed Mahmoud Tareq
Hegazy Maha A.
Mohamed Ekram H.
author_facet Abdelwahed Mahmoud Tareq
Hegazy Maha A.
Mohamed Ekram H.
author_sort Abdelwahed Mahmoud Tareq
collection DOAJ
description Ashwagandha (Withania somnifera) is a very popular medicinal herb originated mainly in India and found in the Middle East and parts of Africa. Ashwagandha has gained recognition as the most revered plant in Ayurvedic medicine. Studies indicated that it is used as anxiolytic, anti-inflammatory, antioxidant, adaptogen, memory enhancer, and possess an effect on neurodegenerative diseases. Additionally, it was revealed that the plant exerts antibacterial, antiviral, antitumor, aphrodisiac, and cardiovascular protection activities. Due to the biological and nutritional importance of nutraceuticals, particularly ashwagandha, and as part of the ongoing research of the natural products and its bioactive phytochemicals, this review aims to summarize the recent analytical techniques that have been reported for the determination of different chemical constituents of Withania somnifera quantitatively and qualitatively, and to highlight new challenges.
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spelling doaj.art-9063131941f74dbe9d189bdbb460c97c2023-04-11T17:07:19ZengDe GruyterReviews in Analytical Chemistry2191-01892023-03-014212536610.1515/revac-2022-0055Major biochemical constituents of Withania somnifera (ashwagandha) extract: A review of chemical analysisAbdelwahed Mahmoud Tareq0Hegazy Maha A.1Mohamed Ekram H.2Pharmaceutical Chemistry Department, Faculty of Pharmacy, The British University in Egypt (BUE), Cairo, EgyptAnalytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr-El Aini Street, 11562 Cairo, EgyptPharmaceutical Chemistry Department, Faculty of Pharmacy, The British University in Egypt (BUE), Cairo, EgyptAshwagandha (Withania somnifera) is a very popular medicinal herb originated mainly in India and found in the Middle East and parts of Africa. Ashwagandha has gained recognition as the most revered plant in Ayurvedic medicine. Studies indicated that it is used as anxiolytic, anti-inflammatory, antioxidant, adaptogen, memory enhancer, and possess an effect on neurodegenerative diseases. Additionally, it was revealed that the plant exerts antibacterial, antiviral, antitumor, aphrodisiac, and cardiovascular protection activities. Due to the biological and nutritional importance of nutraceuticals, particularly ashwagandha, and as part of the ongoing research of the natural products and its bioactive phytochemicals, this review aims to summarize the recent analytical techniques that have been reported for the determination of different chemical constituents of Withania somnifera quantitatively and qualitatively, and to highlight new challenges.https://doi.org/10.1515/revac-2022-0055withania somniferaashwagandhachemical analysisliquid chromatographyspectroscopy
spellingShingle Abdelwahed Mahmoud Tareq
Hegazy Maha A.
Mohamed Ekram H.
Major biochemical constituents of Withania somnifera (ashwagandha) extract: A review of chemical analysis
Reviews in Analytical Chemistry
withania somnifera
ashwagandha
chemical analysis
liquid chromatography
spectroscopy
title Major biochemical constituents of Withania somnifera (ashwagandha) extract: A review of chemical analysis
title_full Major biochemical constituents of Withania somnifera (ashwagandha) extract: A review of chemical analysis
title_fullStr Major biochemical constituents of Withania somnifera (ashwagandha) extract: A review of chemical analysis
title_full_unstemmed Major biochemical constituents of Withania somnifera (ashwagandha) extract: A review of chemical analysis
title_short Major biochemical constituents of Withania somnifera (ashwagandha) extract: A review of chemical analysis
title_sort major biochemical constituents of withania somnifera ashwagandha extract a review of chemical analysis
topic withania somnifera
ashwagandha
chemical analysis
liquid chromatography
spectroscopy
url https://doi.org/10.1515/revac-2022-0055
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