AVE 0991 attenuates oxidative stress and neuronal apoptosis via Mas/PKA/CREB/UCP-2 pathway after subarachnoid hemorrhage in rats

AVE 0991 attenuates oxidative stress and neuronal apoptosis via Mas/PKA/CREB/UCP-2 pathway after subarachnoid hemorrhage in rats

Oxidative stress and neuronal apoptosis have been demonstrated to be key features in early brain injury (EBI) after subarachnoid hemorrhage (SAH). Previous studies have indicated that Mas receptor activation initiates an anti-oxidative and anti-apoptotic role in the brain. However, whether Mas activ...

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Bibliographic Details
Main Authors: Jun Mo, Budbazar Enkhjargal, Zachary D. Travis, Keren Zhou, Pei Wu, Guangyu Zhang, Qiquan Zhu, Tongyu Zhang, Jianhua Peng, Weilin Xu, Umut Ocak, Yili Chen, Jiping Tang, Jianmin Zhang, John H. Zhang
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718306785

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