p53 Immunohistochemistry and Mutation Types Mismatching in High-Grade Serous Ovarian Cancer

p53 Immunohistochemistry and Mutation Types Mismatching in High-Grade Serous Ovarian Cancer

High-grade serous carcinoma (HGSCa) of the ovary is featured by <i>TP53</i> gene mutation. Missense or nonsense mutation types accompany most cases of HGSCa that correlate well with immunohistochemical (IHC) staining results—an all (missense) or none (nonsense) pattern. However, some IHC...

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Bibliographic Details
Main Authors: Eunhyang Park, Hyunho Han, Sung-Eun Choi, Hyunjin Park, Ha-Young Woo, Mi Jang, Hyo-Sup Shim, Sohyun Hwang, Haeyoun Kang, Nam-Hoon Cho
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Diagnostics
Subjects:
p53
immunohistochemistry
next generation sequencing
oligomerization domain
Online Access:https://www.mdpi.com/2075-4418/12/3/579

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