Comparison of machine learning algorithms to SAPS II in predicting in-hospital mortality of fractures of the pelvis and acetabulum: analyzes based on MIMIC-III database

Fractures of pelvis and acetabulum are at high risk of death worldwide. However, the capability of mortality prediction by the conventional system Simple Acute Physiologic Score (SAPS) II remains limited. Here, we hypothesized that the use of machine learning (ML) algorithms could provide better per...

Full description

Bibliographic Details
Main Authors: Xiang Jiang, Weifan Dai, Yanrong Cai
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:All Life
Subjects:
Online Access:http://dx.doi.org/10.1080/26895293.2022.2125448
_version_ 1797236937159868416
author Xiang Jiang
Weifan Dai
Yanrong Cai
author_facet Xiang Jiang
Weifan Dai
Yanrong Cai
author_sort Xiang Jiang
collection DOAJ
description Fractures of pelvis and acetabulum are at high risk of death worldwide. However, the capability of mortality prediction by the conventional system Simple Acute Physiologic Score (SAPS) II remains limited. Here, we hypothesized that the use of machine learning (ML) algorithms could provide better performance of prediction than SAPS II for traumatic patients in the intensive care unit (ICU). Customized ML models were built including support vector machine, decision tree, logistic regression and random forest based on MIMIC-III clinical database. 307 patients were enrolled with an ICD-9 diagnosis of pelvic, acetabular or combined pelvic and acetabular fractures. Feature expansion method was used for experimental models by extending SAPS II features to the first 72 hours after ICU admission, compared with the traditional first-24-hours ones that were used to build respective control models. A comparison of each model’s performance was made through the area under the receiver-operating characteristic curve (AUROC). All the ML models outperformed SAPS II system (AUROC = 0.73), among which the experimental random forest model had the supreme performance (AUROC of 0.90). The results suggested that ML models could aid in better performance of mortality prediction for pelvic and acetabular injuries and potentially support decision-making for orthopedics and ICU practitioners.
first_indexed 2024-03-08T16:58:59Z
format Article
id doaj.art-9068f7bd95cb4a099c3d67b6ef3a78e2
institution Directory Open Access Journal
issn 2689-5307
language English
last_indexed 2024-04-24T17:11:47Z
publishDate 2022-12-01
publisher Taylor & Francis Group
record_format Article
series All Life
spelling doaj.art-9068f7bd95cb4a099c3d67b6ef3a78e22024-03-28T09:48:51ZengTaylor & Francis GroupAll Life2689-53072022-12-011511000101210.1080/26895293.2022.21254482125448Comparison of machine learning algorithms to SAPS II in predicting in-hospital mortality of fractures of the pelvis and acetabulum: analyzes based on MIMIC-III databaseXiang Jiang0Weifan Dai1Yanrong Cai2Tongji University School of MedicineDecathlon InternationalUniversity of HeidelbergFractures of pelvis and acetabulum are at high risk of death worldwide. However, the capability of mortality prediction by the conventional system Simple Acute Physiologic Score (SAPS) II remains limited. Here, we hypothesized that the use of machine learning (ML) algorithms could provide better performance of prediction than SAPS II for traumatic patients in the intensive care unit (ICU). Customized ML models were built including support vector machine, decision tree, logistic regression and random forest based on MIMIC-III clinical database. 307 patients were enrolled with an ICD-9 diagnosis of pelvic, acetabular or combined pelvic and acetabular fractures. Feature expansion method was used for experimental models by extending SAPS II features to the first 72 hours after ICU admission, compared with the traditional first-24-hours ones that were used to build respective control models. A comparison of each model’s performance was made through the area under the receiver-operating characteristic curve (AUROC). All the ML models outperformed SAPS II system (AUROC = 0.73), among which the experimental random forest model had the supreme performance (AUROC of 0.90). The results suggested that ML models could aid in better performance of mortality prediction for pelvic and acetabular injuries and potentially support decision-making for orthopedics and ICU practitioners.http://dx.doi.org/10.1080/26895293.2022.2125448mortality predictionpelvic traumaacetabular fracturessaps iimimicmachine learning (ml)
spellingShingle Xiang Jiang
Weifan Dai
Yanrong Cai
Comparison of machine learning algorithms to SAPS II in predicting in-hospital mortality of fractures of the pelvis and acetabulum: analyzes based on MIMIC-III database
All Life
mortality prediction
pelvic trauma
acetabular fractures
saps ii
mimic
machine learning (ml)
title Comparison of machine learning algorithms to SAPS II in predicting in-hospital mortality of fractures of the pelvis and acetabulum: analyzes based on MIMIC-III database
title_full Comparison of machine learning algorithms to SAPS II in predicting in-hospital mortality of fractures of the pelvis and acetabulum: analyzes based on MIMIC-III database
title_fullStr Comparison of machine learning algorithms to SAPS II in predicting in-hospital mortality of fractures of the pelvis and acetabulum: analyzes based on MIMIC-III database
title_full_unstemmed Comparison of machine learning algorithms to SAPS II in predicting in-hospital mortality of fractures of the pelvis and acetabulum: analyzes based on MIMIC-III database
title_short Comparison of machine learning algorithms to SAPS II in predicting in-hospital mortality of fractures of the pelvis and acetabulum: analyzes based on MIMIC-III database
title_sort comparison of machine learning algorithms to saps ii in predicting in hospital mortality of fractures of the pelvis and acetabulum analyzes based on mimic iii database
topic mortality prediction
pelvic trauma
acetabular fractures
saps ii
mimic
machine learning (ml)
url http://dx.doi.org/10.1080/26895293.2022.2125448
work_keys_str_mv AT xiangjiang comparisonofmachinelearningalgorithmstosapsiiinpredictinginhospitalmortalityoffracturesofthepelvisandacetabulumanalyzesbasedonmimiciiidatabase
AT weifandai comparisonofmachinelearningalgorithmstosapsiiinpredictinginhospitalmortalityoffracturesofthepelvisandacetabulumanalyzesbasedonmimiciiidatabase
AT yanrongcai comparisonofmachinelearningalgorithmstosapsiiinpredictinginhospitalmortalityoffracturesofthepelvisandacetabulumanalyzesbasedonmimiciiidatabase