Paradoxical results of two automated real-time PCR assays in the diagnosis of pleural tuberculosis

Tuberculosis (TB) is a major cause of worldwide mortality. We report the case of a non-HIV-infected woman with clinical suspicion of pleural tuberculosis and contradictory results between Xpert® MTB/RIF and Abbott RealTime MTB assays from pleural fluid specimen. Liquid and solid cultures for tubercu...

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Bibliographic Details
Main Authors: Soraya E. Morales-López, Jayr A. Yepes, Irina Anzola, Hernán Aponte, Claudia R. Llerena-Polo
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:International Journal of Infectious Diseases
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Online Access:http://www.sciencedirect.com/science/article/pii/S1201971216312292
Description
Summary:Tuberculosis (TB) is a major cause of worldwide mortality. We report the case of a non-HIV-infected woman with clinical suspicion of pleural tuberculosis and contradictory results between Xpert® MTB/RIF and Abbott RealTime MTB assays from pleural fluid specimen. Liquid and solid cultures for tuberculosis were performed with negative results. The patient received treatment, and clinical improvement was observed. Both techniques detect Mycobacterium tuberculosis complex, but they have different targets and limits of detection. Abbott RealTime MTB results correlated well with the clinical findings of the patient.
ISSN:1201-9712
1878-3511