Paradoxical results of two automated real-time PCR assays in the diagnosis of pleural tuberculosis
Tuberculosis (TB) is a major cause of worldwide mortality. We report the case of a non-HIV-infected woman with clinical suspicion of pleural tuberculosis and contradictory results between Xpert® MTB/RIF and Abbott RealTime MTB assays from pleural fluid specimen. Liquid and solid cultures for tubercu...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2017-01-01
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| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971216312292 |
| _version_ | 1818931921266147328 |
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| author | Soraya E. Morales-López Jayr A. Yepes Irina Anzola Hernán Aponte Claudia R. Llerena-Polo |
| author_facet | Soraya E. Morales-López Jayr A. Yepes Irina Anzola Hernán Aponte Claudia R. Llerena-Polo |
| author_sort | Soraya E. Morales-López |
| collection | DOAJ |
| description | Tuberculosis (TB) is a major cause of worldwide mortality. We report the case of a non-HIV-infected woman with clinical suspicion of pleural tuberculosis and contradictory results between Xpert® MTB/RIF and Abbott RealTime MTB assays from pleural fluid specimen. Liquid and solid cultures for tuberculosis were performed with negative results. The patient received treatment, and clinical improvement was observed. Both techniques detect Mycobacterium tuberculosis complex, but they have different targets and limits of detection. Abbott RealTime MTB results correlated well with the clinical findings of the patient. |
| first_indexed | 2024-12-20T04:24:16Z |
| format | Article |
| id | doaj.art-90694b032acb44a3a19fa9aa316105b3 |
| institution | Directory Open Access Journal |
| issn | 1201-9712 1878-3511 |
| language | English |
| last_indexed | 2024-12-20T04:24:16Z |
| publishDate | 2017-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-90694b032acb44a3a19fa9aa316105b32022-12-21T19:53:34ZengElsevierInternational Journal of Infectious Diseases1201-97121878-35112017-01-0154C363810.1016/j.ijid.2016.11.011Paradoxical results of two automated real-time PCR assays in the diagnosis of pleural tuberculosisSoraya E. Morales-López0Jayr A. Yepes1Irina Anzola2Hernán Aponte3Claudia R. Llerena-Polo4Laboratorios Nancy Flórez García S.A.S., Valledupar, ColombiaPrograma de Microbiología. Universidad Popular del Cesar, Valledupar, ColombiaLaboratorios Nancy Flórez García S.A.S., Valledupar, ColombiaHospital Rosario Pumarejo de López, Valledupar, ColombiaGrupo Micobacterias. Instituto Nacional de Salud, Bogotá, ColombiaTuberculosis (TB) is a major cause of worldwide mortality. We report the case of a non-HIV-infected woman with clinical suspicion of pleural tuberculosis and contradictory results between Xpert® MTB/RIF and Abbott RealTime MTB assays from pleural fluid specimen. Liquid and solid cultures for tuberculosis were performed with negative results. The patient received treatment, and clinical improvement was observed. Both techniques detect Mycobacterium tuberculosis complex, but they have different targets and limits of detection. Abbott RealTime MTB results correlated well with the clinical findings of the patient.http://www.sciencedirect.com/science/article/pii/S1201971216312292pleural tuberculosisColombiaAbbott RealTime MTBXpert MTB/RIF |
| spellingShingle | Soraya E. Morales-López Jayr A. Yepes Irina Anzola Hernán Aponte Claudia R. Llerena-Polo Paradoxical results of two automated real-time PCR assays in the diagnosis of pleural tuberculosis International Journal of Infectious Diseases pleural tuberculosis Colombia Abbott RealTime MTB Xpert MTB/RIF |
| title | Paradoxical results of two automated real-time PCR assays in the diagnosis of pleural tuberculosis |
| title_full | Paradoxical results of two automated real-time PCR assays in the diagnosis of pleural tuberculosis |
| title_fullStr | Paradoxical results of two automated real-time PCR assays in the diagnosis of pleural tuberculosis |
| title_full_unstemmed | Paradoxical results of two automated real-time PCR assays in the diagnosis of pleural tuberculosis |
| title_short | Paradoxical results of two automated real-time PCR assays in the diagnosis of pleural tuberculosis |
| title_sort | paradoxical results of two automated real time pcr assays in the diagnosis of pleural tuberculosis |
| topic | pleural tuberculosis Colombia Abbott RealTime MTB Xpert MTB/RIF |
| url | http://www.sciencedirect.com/science/article/pii/S1201971216312292 |
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