Improving the Accuracy of the Effective Atomic Number (EAN) and Relative Electron Density (RED) with Stoichiometric Calibration on PCD-CT Images

The photon counting detector (PCD) in computed tomography (CT) can count the number of incoming photons in order to obtain energy information for photons corresponding to user-defined thresholds. Research on the extraction of effective atomic number (EAN) and relative electron density (RED) using du...

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Main Authors: Kihong Son, Daehong Kim, Sooyeul Lee
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/22/23/9220
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author Kihong Son
Daehong Kim
Sooyeul Lee
author_facet Kihong Son
Daehong Kim
Sooyeul Lee
author_sort Kihong Son
collection DOAJ
description The photon counting detector (PCD) in computed tomography (CT) can count the number of incoming photons in order to obtain energy information for photons corresponding to user-defined thresholds. Research on the extraction of effective atomic number (EAN) and relative electron density (RED) using dual-energy CT (DECT) is currently underway. This study proposes a method for improving EAN and RED accuracy of tissue-equivalent materials by using PCD-CT-based stoichiometric calibration. After obtaining DECT images in energy bin (EB) and full spectrum (FS) modes for eight tissue-equivalent materials, the EAN was calculated with stoichiometric calibration. Using the EAN image, the RED image was acquired to evaluate the accuracy. The errors of both EAN and RED obtained with EB were within 4%. In particular, the accuracy of RED was higher than that of the FS method. Study results indicate that PCD-CT contributes to improving EAN and RED accuracy. Further studies will be aimed at reducing ring artifacts by pixel-correcting PCD images and improving stopping power ratio (SPR) measurements for dose calculation in particle therapy.
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spelling doaj.art-90698b57116641a78aaef1fa0df12fe12023-11-24T12:10:33ZengMDPI AGSensors1424-82202022-11-012223922010.3390/s22239220Improving the Accuracy of the Effective Atomic Number (EAN) and Relative Electron Density (RED) with Stoichiometric Calibration on PCD-CT ImagesKihong Son0Daehong Kim1Sooyeul Lee2Medical Information Research Section, Electronics and Telecommunications Research Institute, Daejeon 34129, Republic of KoreaDepartment of Radiological Science, Eulji University, Seongnam 13135, Republic of KoreaMedical Information Research Section, Electronics and Telecommunications Research Institute, Daejeon 34129, Republic of KoreaThe photon counting detector (PCD) in computed tomography (CT) can count the number of incoming photons in order to obtain energy information for photons corresponding to user-defined thresholds. Research on the extraction of effective atomic number (EAN) and relative electron density (RED) using dual-energy CT (DECT) is currently underway. This study proposes a method for improving EAN and RED accuracy of tissue-equivalent materials by using PCD-CT-based stoichiometric calibration. After obtaining DECT images in energy bin (EB) and full spectrum (FS) modes for eight tissue-equivalent materials, the EAN was calculated with stoichiometric calibration. Using the EAN image, the RED image was acquired to evaluate the accuracy. The errors of both EAN and RED obtained with EB were within 4%. In particular, the accuracy of RED was higher than that of the FS method. Study results indicate that PCD-CT contributes to improving EAN and RED accuracy. Further studies will be aimed at reducing ring artifacts by pixel-correcting PCD images and improving stopping power ratio (SPR) measurements for dose calculation in particle therapy.https://www.mdpi.com/1424-8220/22/23/9220PCD-CTdual-energyEANREDstoichiometric calibration
spellingShingle Kihong Son
Daehong Kim
Sooyeul Lee
Improving the Accuracy of the Effective Atomic Number (EAN) and Relative Electron Density (RED) with Stoichiometric Calibration on PCD-CT Images
Sensors
PCD-CT
dual-energy
EAN
RED
stoichiometric calibration
title Improving the Accuracy of the Effective Atomic Number (EAN) and Relative Electron Density (RED) with Stoichiometric Calibration on PCD-CT Images
title_full Improving the Accuracy of the Effective Atomic Number (EAN) and Relative Electron Density (RED) with Stoichiometric Calibration on PCD-CT Images
title_fullStr Improving the Accuracy of the Effective Atomic Number (EAN) and Relative Electron Density (RED) with Stoichiometric Calibration on PCD-CT Images
title_full_unstemmed Improving the Accuracy of the Effective Atomic Number (EAN) and Relative Electron Density (RED) with Stoichiometric Calibration on PCD-CT Images
title_short Improving the Accuracy of the Effective Atomic Number (EAN) and Relative Electron Density (RED) with Stoichiometric Calibration on PCD-CT Images
title_sort improving the accuracy of the effective atomic number ean and relative electron density red with stoichiometric calibration on pcd ct images
topic PCD-CT
dual-energy
EAN
RED
stoichiometric calibration
url https://www.mdpi.com/1424-8220/22/23/9220
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AT daehongkim improvingtheaccuracyoftheeffectiveatomicnumbereanandrelativeelectrondensityredwithstoichiometriccalibrationonpcdctimages
AT sooyeullee improvingtheaccuracyoftheeffectiveatomicnumbereanandrelativeelectrondensityredwithstoichiometriccalibrationonpcdctimages