Severe Generalized Periodontitis in a Patient with an Aplastic Anemia: a 5 Year Follow-up Case Report

Aplastic anemia is a hematological disorder characterized by pancytopenia. This case report presents a young patient with untreated periodontitis associated with hematological disorders, and cyclosporine therapy. During 2 consecutive days, periodontal therapy which consisted of nonsurgical therapy...

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Main Authors: Ivan Puhar, Darko Božić, Domagoj Žabarović, Damir Jelušić, Darije Plančak
Format: Article
Language:English
Published: University of Zagreb. School of Dental Medicine 2015-01-01
Series:Acta Stomatologica Croatica
Subjects:
Online Access:https://hrcak.srce.hr/file/206555
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author Ivan Puhar
Darko Božić
Domagoj Žabarović
Damir Jelušić
Darije Plančak
author_facet Ivan Puhar
Darko Božić
Domagoj Žabarović
Damir Jelušić
Darije Plančak
author_sort Ivan Puhar
collection DOAJ
description Aplastic anemia is a hematological disorder characterized by pancytopenia. This case report presents a young patient with untreated periodontitis associated with hematological disorders, and cyclosporine therapy. During 2 consecutive days, periodontal therapy which consisted of nonsurgical therapy supplemented with an antibiotic treatment and antifibrinolytic therapy was performed. Commercial microbiological PCR tests and periodontitis IL-1 polymorphism risk test were performed. Following the periodontal therapy, the inflammation was resolved and the patient’s occlusion was restored by means of removable partial dentures. After the 5 year follow-up, the patient still remained with shallow probing depths although there was inadequate compliance during the maintenance phase. Aplastic anemia increases the risk of onset of severe forms of periodontitis that can be additionally complicated with cyclosporine therapy. In such patients, periodontal therapy must be supplemented with antibiotics.
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spelling doaj.art-906cef21a25a4a58a6b32f4e7776c99b2024-04-15T13:40:42ZengUniversity of Zagreb. School of Dental MedicineActa Stomatologica Croatica0001-70191846-04102015-01-0149215115710.15644/asc49/2/9Severe Generalized Periodontitis in a Patient with an Aplastic Anemia: a 5 Year Follow-up Case ReportIvan Puhar0Darko Božić1Domagoj Žabarović2Damir Jelušić3Darije Plančak4Department of Periodontology, School of Dental Medicine, Zagreb, CroatiaDepartment of Periodontology, School of Dental Medicine, Zagreb, CroatiaDepartment of Mobile Prosthodontics, School of Dental Medicine, Zagreb, CroatiaDental Polyclinic “Dr Jelušić”, Opatija, CroatiaDepartment of Periodontology, School of Dental Medicine, Zagreb, CroatiaAplastic anemia is a hematological disorder characterized by pancytopenia. This case report presents a young patient with untreated periodontitis associated with hematological disorders, and cyclosporine therapy. During 2 consecutive days, periodontal therapy which consisted of nonsurgical therapy supplemented with an antibiotic treatment and antifibrinolytic therapy was performed. Commercial microbiological PCR tests and periodontitis IL-1 polymorphism risk test were performed. Following the periodontal therapy, the inflammation was resolved and the patient’s occlusion was restored by means of removable partial dentures. After the 5 year follow-up, the patient still remained with shallow probing depths although there was inadequate compliance during the maintenance phase. Aplastic anemia increases the risk of onset of severe forms of periodontitis that can be additionally complicated with cyclosporine therapy. In such patients, periodontal therapy must be supplemented with antibiotics.https://hrcak.srce.hr/file/206555Anemia, AplasticPancytopeniaCyclosporineAntifibrinolytic AgentsGingival hyperplasiaPeriodontitis
spellingShingle Ivan Puhar
Darko Božić
Domagoj Žabarović
Damir Jelušić
Darije Plančak
Severe Generalized Periodontitis in a Patient with an Aplastic Anemia: a 5 Year Follow-up Case Report
Acta Stomatologica Croatica
Anemia, Aplastic
Pancytopenia
Cyclosporine
Antifibrinolytic Agents
Gingival hyperplasia
Periodontitis
title Severe Generalized Periodontitis in a Patient with an Aplastic Anemia: a 5 Year Follow-up Case Report
title_full Severe Generalized Periodontitis in a Patient with an Aplastic Anemia: a 5 Year Follow-up Case Report
title_fullStr Severe Generalized Periodontitis in a Patient with an Aplastic Anemia: a 5 Year Follow-up Case Report
title_full_unstemmed Severe Generalized Periodontitis in a Patient with an Aplastic Anemia: a 5 Year Follow-up Case Report
title_short Severe Generalized Periodontitis in a Patient with an Aplastic Anemia: a 5 Year Follow-up Case Report
title_sort severe generalized periodontitis in a patient with an aplastic anemia a 5 year follow up case report
topic Anemia, Aplastic
Pancytopenia
Cyclosporine
Antifibrinolytic Agents
Gingival hyperplasia
Periodontitis
url https://hrcak.srce.hr/file/206555
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