Neostigmine induced coronary artery spasm: A case report and literature review
Neostigmine is a cholinesterase inhibitor which does not cross the blood brain barrier and a commonly used for reversal of nondepolarizing muscle relaxants. In the following case report, we present a patient who developed coronary artery spasm, after the administration of repeated doses of neostigmi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Journal of Anaesthesiology Clinical Pharmacology |
| Subjects: | |
| Online Access: | http://www.joacp.org/article.asp?issn=0970-9185;year=2017;volume=33;issue=3;spage=402;epage=405;aulast=Kolker |
| _version_ | 1818292236441354240 |
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| author | Shimon Kolker Dan Tzivoni David Rosenmann Shmuel Meyler Alexander Ioscovich |
| author_facet | Shimon Kolker Dan Tzivoni David Rosenmann Shmuel Meyler Alexander Ioscovich |
| author_sort | Shimon Kolker |
| collection | DOAJ |
| description | Neostigmine is a cholinesterase inhibitor which does not cross the blood brain barrier and a commonly used for reversal of nondepolarizing muscle relaxants. In the following case report, we present a patient who developed coronary artery spasm, after the administration of repeated doses of neostigmine. Ours is the first case to demonstrate such a longstanding coronary artery vasospasm that lasted several hours in response to neostigmine, resulting in myocardial damage and left ventricular dysfunction. We would like to draw the attention of the anesthesiologists to this rare effect that may lead to perioperative cardiac complications. |
| first_indexed | 2024-12-13T02:56:45Z |
| format | Article |
| id | doaj.art-906da756d66241c8b340ec3563faf949 |
| institution | Directory Open Access Journal |
| issn | 0970-9185 |
| language | English |
| last_indexed | 2024-12-13T02:56:45Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Anaesthesiology Clinical Pharmacology |
| spelling | doaj.art-906da756d66241c8b340ec3563faf9492022-12-22T00:01:56ZengWolters Kluwer Medknow PublicationsJournal of Anaesthesiology Clinical Pharmacology0970-91852017-01-0133340240510.4103/0970-9185.173337Neostigmine induced coronary artery spasm: A case report and literature reviewShimon KolkerDan TzivoniDavid RosenmannShmuel MeylerAlexander IoscovichNeostigmine is a cholinesterase inhibitor which does not cross the blood brain barrier and a commonly used for reversal of nondepolarizing muscle relaxants. In the following case report, we present a patient who developed coronary artery spasm, after the administration of repeated doses of neostigmine. Ours is the first case to demonstrate such a longstanding coronary artery vasospasm that lasted several hours in response to neostigmine, resulting in myocardial damage and left ventricular dysfunction. We would like to draw the attention of the anesthesiologists to this rare effect that may lead to perioperative cardiac complications.http://www.joacp.org/article.asp?issn=0970-9185;year=2017;volume=33;issue=3;spage=402;epage=405;aulast=KolkerAnesthesiacardiologycomplicationmuscle relaxantspostoperative care |
| spellingShingle | Shimon Kolker Dan Tzivoni David Rosenmann Shmuel Meyler Alexander Ioscovich Neostigmine induced coronary artery spasm: A case report and literature review Journal of Anaesthesiology Clinical Pharmacology Anesthesia cardiology complication muscle relaxants postoperative care |
| title | Neostigmine induced coronary artery spasm: A case report and literature review |
| title_full | Neostigmine induced coronary artery spasm: A case report and literature review |
| title_fullStr | Neostigmine induced coronary artery spasm: A case report and literature review |
| title_full_unstemmed | Neostigmine induced coronary artery spasm: A case report and literature review |
| title_short | Neostigmine induced coronary artery spasm: A case report and literature review |
| title_sort | neostigmine induced coronary artery spasm a case report and literature review |
| topic | Anesthesia cardiology complication muscle relaxants postoperative care |
| url | http://www.joacp.org/article.asp?issn=0970-9185;year=2017;volume=33;issue=3;spage=402;epage=405;aulast=Kolker |
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