Surface frustration re-patterning underlies the structural landscape and evolvability of fungal orphan candidate effectors

Abstract Pathogens secrete effector proteins to subvert host physiology and cause disease. Effectors are engaged in a molecular arms race with the host resulting in conflicting evolutionary constraints to manipulate host cells without triggering immune responses. The molecular mechanisms allowing ef...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Mark C. Derbyshire, Sylvain Raffaele
Format: Artikel
Sprache:English
Veröffentlicht: Nature Portfolio 2023-08-01
Schriftenreihe:Nature Communications
Online Zugang:https://doi.org/10.1038/s41467-023-40949-9