Surface frustration re-patterning underlies the structural landscape and evolvability of fungal orphan candidate effectors
Abstract Pathogens secrete effector proteins to subvert host physiology and cause disease. Effectors are engaged in a molecular arms race with the host resulting in conflicting evolutionary constraints to manipulate host cells without triggering immune responses. The molecular mechanisms allowing ef...
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Format: | Artikel |
Sprache: | English |
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Nature Portfolio
2023-08-01
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Schriftenreihe: | Nature Communications |
Online Zugang: | https://doi.org/10.1038/s41467-023-40949-9 |