Ladder-based resistance training with the progression of training load altered the tibial nerve ultrastructure and muscle fiber area without altering the morphology of the postsynaptic compartment
Scientific evidence regarding the effect of different ladder-based resistance training (LRT) protocols on the morphology of the neuromuscular system is scarce. Therefore, the present study aimed to compare the morphological response induced by different LRT protocols in the ultrastructure of the tib...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-04-01
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| Series: | Frontiers in Physiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2024.1371839/full |
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| author | Walter Krause Neto Wellington Silva Tony Oliveira Alan Vilas Boas Adriano Ciena Érico Chagas Caperuto Eliane Florencio Gama |
| author_facet | Walter Krause Neto Wellington Silva Tony Oliveira Alan Vilas Boas Adriano Ciena Érico Chagas Caperuto Eliane Florencio Gama |
| author_sort | Walter Krause Neto |
| collection | DOAJ |
| description | Scientific evidence regarding the effect of different ladder-based resistance training (LRT) protocols on the morphology of the neuromuscular system is scarce. Therefore, the present study aimed to compare the morphological response induced by different LRT protocols in the ultrastructure of the tibial nerve and morphology of the motor endplate and muscle fibers of the soleus and plantaris muscles of young adult Wistar rats. Rats were divided into groups: sedentary control (control, n = 9), a predetermined number of climbs and progressive submaximal intensity (fixed, n = 9), high-intensity and high-volume pyramidal system with a predetermined number of climbs (Pyramid, n = 9) and lrt with a high-intensity pyramidal system to exhaustion (failure, n = 9). myelinated fibers and myelin sheath thickness were statistically larger in pyramid, fixed, and failure. myelinated axons were statistically larger in pyramid than in control. schwann cell nuclei were statistically larger in pyramid, fixed, and failure. microtubules and neurofilaments were greater in pyramid than in control. morphological analysis of the postsynaptic component of the plantar and soleus muscles did not indicate any significant difference. for plantaris, the type i myofibers were statistically larger in the pyramid and fixed compared to control. the pyramid, fixed, and failure groups for type ii myofibers had larger csa than control. for soleus, the type i myofibers were statistically larger in the pyramid than in control. pyramid and fixed had larger csa for type ii myofibers than control and failure. the pyramid and fixed groups showed greater mass progression delta than the failure. We concluded that the LRT protocols with greater volume and progression of accumulated mass elicit more significant changes in the ultrastructure of the tibial nerve and muscle hypertrophy without endplate changes. |
| first_indexed | 2024-04-24T08:10:43Z |
| format | Article |
| id | doaj.art-906f969bf4bb4a5cbf2918f18d7c8020 |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-04-24T08:10:43Z |
| publishDate | 2024-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-906f969bf4bb4a5cbf2918f18d7c80202024-04-17T04:56:51ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2024-04-011510.3389/fphys.2024.13718391371839Ladder-based resistance training with the progression of training load altered the tibial nerve ultrastructure and muscle fiber area without altering the morphology of the postsynaptic compartmentWalter Krause Neto0Wellington Silva1Tony Oliveira2Alan Vilas Boas3Adriano Ciena4Érico Chagas Caperuto5Eliane Florencio Gama6Department of Morphology and Genetics, Universidade Federal de São Paulo, São Paulo, BrazilDepatment of Physical Education, Laboratory of Human Movement, Universidade São Judas Tadeu, São Paulo, BrazilDepatment of Physical Education, Laboratory of Human Movement, Universidade São Judas Tadeu, São Paulo, BrazilDepatment of Physical Education, Laboratory of Human Movement, Universidade São Judas Tadeu, São Paulo, BrazilDepartment of Physical Education, Laboratory of Morphology and Physical Activity, Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo, BrazilDepatment of Physical Education, Laboratory of Human Movement, Universidade São Judas Tadeu, São Paulo, BrazilDepartment of Morphology and Genetics, Universidade Federal de São Paulo, São Paulo, BrazilScientific evidence regarding the effect of different ladder-based resistance training (LRT) protocols on the morphology of the neuromuscular system is scarce. Therefore, the present study aimed to compare the morphological response induced by different LRT protocols in the ultrastructure of the tibial nerve and morphology of the motor endplate and muscle fibers of the soleus and plantaris muscles of young adult Wistar rats. Rats were divided into groups: sedentary control (control, n = 9), a predetermined number of climbs and progressive submaximal intensity (fixed, n = 9), high-intensity and high-volume pyramidal system with a predetermined number of climbs (Pyramid, n = 9) and lrt with a high-intensity pyramidal system to exhaustion (failure, n = 9). myelinated fibers and myelin sheath thickness were statistically larger in pyramid, fixed, and failure. myelinated axons were statistically larger in pyramid than in control. schwann cell nuclei were statistically larger in pyramid, fixed, and failure. microtubules and neurofilaments were greater in pyramid than in control. morphological analysis of the postsynaptic component of the plantar and soleus muscles did not indicate any significant difference. for plantaris, the type i myofibers were statistically larger in the pyramid and fixed compared to control. the pyramid, fixed, and failure groups for type ii myofibers had larger csa than control. for soleus, the type i myofibers were statistically larger in the pyramid than in control. pyramid and fixed had larger csa for type ii myofibers than control and failure. the pyramid and fixed groups showed greater mass progression delta than the failure. We concluded that the LRT protocols with greater volume and progression of accumulated mass elicit more significant changes in the ultrastructure of the tibial nerve and muscle hypertrophy without endplate changes.https://www.frontiersin.org/articles/10.3389/fphys.2024.1371839/fullexercisetibial nervemotor unitneuromuscular junctionskeletal muscles |
| spellingShingle | Walter Krause Neto Wellington Silva Tony Oliveira Alan Vilas Boas Adriano Ciena Érico Chagas Caperuto Eliane Florencio Gama Ladder-based resistance training with the progression of training load altered the tibial nerve ultrastructure and muscle fiber area without altering the morphology of the postsynaptic compartment Frontiers in Physiology exercise tibial nerve motor unit neuromuscular junction skeletal muscles |
| title | Ladder-based resistance training with the progression of training load altered the tibial nerve ultrastructure and muscle fiber area without altering the morphology of the postsynaptic compartment |
| title_full | Ladder-based resistance training with the progression of training load altered the tibial nerve ultrastructure and muscle fiber area without altering the morphology of the postsynaptic compartment |
| title_fullStr | Ladder-based resistance training with the progression of training load altered the tibial nerve ultrastructure and muscle fiber area without altering the morphology of the postsynaptic compartment |
| title_full_unstemmed | Ladder-based resistance training with the progression of training load altered the tibial nerve ultrastructure and muscle fiber area without altering the morphology of the postsynaptic compartment |
| title_short | Ladder-based resistance training with the progression of training load altered the tibial nerve ultrastructure and muscle fiber area without altering the morphology of the postsynaptic compartment |
| title_sort | ladder based resistance training with the progression of training load altered the tibial nerve ultrastructure and muscle fiber area without altering the morphology of the postsynaptic compartment |
| topic | exercise tibial nerve motor unit neuromuscular junction skeletal muscles |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2024.1371839/full |
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