Vitamin intake and periodontal disease: a meta-analysis of observational studies
Abstract Objective A meta-analysis was performed to assess the epidemiological correlation between dietary intake of various types of vitamin intake and the risk of periodontal disease. Methods A comprehensive computerized search was conducted in eight databases, namely PubMed, Web of Science, Embas...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-01-01
|
| Series: | BMC Oral Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12903-024-03850-5 |
| _version_ | 1827377072404692992 |
|---|---|
| author | Nannan Mi Miaomiao Zhang Zheng Ying Xiaoping Lin Ying Jin |
| author_facet | Nannan Mi Miaomiao Zhang Zheng Ying Xiaoping Lin Ying Jin |
| author_sort | Nannan Mi |
| collection | DOAJ |
| description | Abstract Objective A meta-analysis was performed to assess the epidemiological correlation between dietary intake of various types of vitamin intake and the risk of periodontal disease. Methods A comprehensive computerized search was conducted in eight databases, namely PubMed, Web of Science, Embase, Cochrane Library, China Biology Medicine Disc, CNKI, VIP, and WanFang Database, and a random effect model was applied to combine pooled odds ratio (ORs) with corresponding 95% confidence intervals (CIs) of the included studies, and the sensitivity analysis was performed to explore the impact of a single study on the comprehensive results. Results We finally included 45 effect groups from 23 observational studies, with a total number of study participants of 74,488. The results showed that higher levels of vitamin A (OR: 0.788, 95% CI: 0.640–0.971), vitamin B complex (OR: 0.884, 95% CI: 0.824–0.948), vitamin C (OR: 0.875, 95% CI: 0.775–0.988), vitamin D (OR: 0.964, 95% CI: 0.948–0.981), and vitamin E (OR: 0.868, 95% CI: 0.776–0.971) intake all were negatively correlated with periodontal disease. After removing each study, leave-one-out sensitivity analysis indicated no significant change in the overall results of any of the five meta-analyses. Conclusions The results from this meta-analysis demonstrated a negative association between high-dose vitamin A, vitamin B complex, vitamin C, vitamin D, and vitamin E consumption and the likelihood of developing periodontal disease, revealing the significant role of vitamins in preventing periodontal disease. |
| first_indexed | 2024-03-08T12:33:31Z |
| format | Article |
| id | doaj.art-9071cc999255413c984c45b4b778822c |
| institution | Directory Open Access Journal |
| issn | 1472-6831 |
| language | English |
| last_indexed | 2024-03-08T12:33:31Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj.art-9071cc999255413c984c45b4b778822c2024-01-21T12:37:52ZengBMCBMC Oral Health1472-68312024-01-0124111410.1186/s12903-024-03850-5Vitamin intake and periodontal disease: a meta-analysis of observational studiesNannan Mi0Miaomiao Zhang1Zheng Ying2Xiaoping Lin3Ying Jin4Department of Stomatology, Shengjing Hospital of China Medical UniversityDepartment of Stomatology, Shengjing Hospital of China Medical UniversityDepartment of Stomatology, Shengjing Hospital of China Medical UniversityDepartment of Stomatology, Shengjing Hospital of China Medical UniversityDepartment of Stomatology, Shengjing Hospital of China Medical UniversityAbstract Objective A meta-analysis was performed to assess the epidemiological correlation between dietary intake of various types of vitamin intake and the risk of periodontal disease. Methods A comprehensive computerized search was conducted in eight databases, namely PubMed, Web of Science, Embase, Cochrane Library, China Biology Medicine Disc, CNKI, VIP, and WanFang Database, and a random effect model was applied to combine pooled odds ratio (ORs) with corresponding 95% confidence intervals (CIs) of the included studies, and the sensitivity analysis was performed to explore the impact of a single study on the comprehensive results. Results We finally included 45 effect groups from 23 observational studies, with a total number of study participants of 74,488. The results showed that higher levels of vitamin A (OR: 0.788, 95% CI: 0.640–0.971), vitamin B complex (OR: 0.884, 95% CI: 0.824–0.948), vitamin C (OR: 0.875, 95% CI: 0.775–0.988), vitamin D (OR: 0.964, 95% CI: 0.948–0.981), and vitamin E (OR: 0.868, 95% CI: 0.776–0.971) intake all were negatively correlated with periodontal disease. After removing each study, leave-one-out sensitivity analysis indicated no significant change in the overall results of any of the five meta-analyses. Conclusions The results from this meta-analysis demonstrated a negative association between high-dose vitamin A, vitamin B complex, vitamin C, vitamin D, and vitamin E consumption and the likelihood of developing periodontal disease, revealing the significant role of vitamins in preventing periodontal disease.https://doi.org/10.1186/s12903-024-03850-5VitaminFolatePeriodontal diseaseMeta-analysis |
| spellingShingle | Nannan Mi Miaomiao Zhang Zheng Ying Xiaoping Lin Ying Jin Vitamin intake and periodontal disease: a meta-analysis of observational studies BMC Oral Health Vitamin Folate Periodontal disease Meta-analysis |
| title | Vitamin intake and periodontal disease: a meta-analysis of observational studies |
| title_full | Vitamin intake and periodontal disease: a meta-analysis of observational studies |
| title_fullStr | Vitamin intake and periodontal disease: a meta-analysis of observational studies |
| title_full_unstemmed | Vitamin intake and periodontal disease: a meta-analysis of observational studies |
| title_short | Vitamin intake and periodontal disease: a meta-analysis of observational studies |
| title_sort | vitamin intake and periodontal disease a meta analysis of observational studies |
| topic | Vitamin Folate Periodontal disease Meta-analysis |
| url | https://doi.org/10.1186/s12903-024-03850-5 |
| work_keys_str_mv | AT nannanmi vitaminintakeandperiodontaldiseaseametaanalysisofobservationalstudies AT miaomiaozhang vitaminintakeandperiodontaldiseaseametaanalysisofobservationalstudies AT zhengying vitaminintakeandperiodontaldiseaseametaanalysisofobservationalstudies AT xiaopinglin vitaminintakeandperiodontaldiseaseametaanalysisofobservationalstudies AT yingjin vitaminintakeandperiodontaldiseaseametaanalysisofobservationalstudies |