Thermoneutral housing attenuates premature cancellous bone loss in male C57BL/6J mice

Thermoneutral housing attenuates premature cancellous bone loss in male C57BL/6J mice

Mice are a commonly used model to investigate aging-related bone loss but, in contrast to humans, mice exhibit cancellous bone loss prior to skeletal maturity. The mechanisms mediating premature bone loss are not well established. However, our previous work in female mice suggests housing temperatur...

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Bibliographic Details
Main Authors: Stephen A Martin, Kenneth A Philbrick, Carmen P Wong, Dawn A Olson, Adam J Branscum, Donald B Jump, Charles K Marik, Jonathan M DenHerder, Jennifer L Sargent, Russell T Turner, Urszula T Iwaniec
Format: Article
Language:English
Published: Bioscientifica 2019-11-01
Series:Endocrine Connections
Subjects:
animal models
sympathetic signaling
thermogenesis
metabolism
bone formation and resorption
Online Access:https://ec.bioscientifica.com/view/journals/ec/8/11/EC-19-0359.xml

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