Preparation of (3R)-quinuclidinol using heterogeneous biocatalytic hydrogenation in a dynamically-mixed continuous flow reactor

Introduction: This work was carried out to understand if a heterogeneous biocatalytic hydrogenation system could be implemented in a slurry mode continuous flow reactor, as a “slot-in” alternative to a metal/carbon catalyst with minimal process or chemical engineering development.Method: Biocatalyti...

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Bibliographic Details
Main Authors: Sarah E. Cleary, Sofia Kazantzi, Joshua A. Trenchard, Martin Monedero, Jack W. Allman, Tara C. Lurshay, Xu Zhao, Michael B. C. Kenny, Holly A. Reeve
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Catalysis
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Online Access:https://www.frontiersin.org/articles/10.3389/fctls.2023.1114536/full

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