Spotlight on MicroPulse Laser Trabeculoplasty in Open-Angle Glaucoma: What’s on? A Review of the Literature

Glaucoma is the most common cause of permanent blindness in the world, caused by a progressive optic neuropathy. Patients with glaucoma are often treated with topical medicines therapy in order to reduce intra-ocular pressure (IOP). On the other hand, laser therapies, with the introduction of Argon...

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Main Authors: Gloria Gambini, Matteo Mario Carlà, Tomaso Caporossi, Umberto De Vico, Alfonso Savastano, Antonio Baldascino, Clara Rizzo, Raphael Kilian, Stanislao Rizzo
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Vision
Subjects:
Online Access:https://www.mdpi.com/2411-5150/6/1/8
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author Gloria Gambini
Matteo Mario Carlà
Tomaso Caporossi
Umberto De Vico
Alfonso Savastano
Antonio Baldascino
Clara Rizzo
Raphael Kilian
Stanislao Rizzo
author_facet Gloria Gambini
Matteo Mario Carlà
Tomaso Caporossi
Umberto De Vico
Alfonso Savastano
Antonio Baldascino
Clara Rizzo
Raphael Kilian
Stanislao Rizzo
author_sort Gloria Gambini
collection DOAJ
description Glaucoma is the most common cause of permanent blindness in the world, caused by a progressive optic neuropathy. Patients with glaucoma are often treated with topical medicines therapy in order to reduce intra-ocular pressure (IOP). On the other hand, laser therapies, with the introduction of Argon Laser Trabeculoplasty (ALT) and successively with Selective Laser Trabeculoplasty (SLT), were reported to be effective in IOP control, with low adverse effect rates. In recent years, the micropulse laser, a subthreshold laser technology, was introduced with the goal of reducing side effects while maintaining the effectiveness of the laser treatments. Several studies focused on Micropulse Diode Laser Trabeculoplasty (MDLT) in open-angle glaucoma, to evaluate its effectiveness and possible side effects. Promising results were reported, but irradiation circumstances have not been standardized yet and its role as a substitute for previous laser techniques has yet to be defined. As a result, the goal of this review was to analyze the physical principles at the basis of MDLT and to frame it in the open-angle glaucoma management setting, highlighting the advantages and shortfalls of this technique.
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spelling doaj.art-907b1d3e94cf4b7d87620722b8b417912023-11-30T22:47:47ZengMDPI AGVision2411-51502022-01-0161810.3390/vision6010008Spotlight on MicroPulse Laser Trabeculoplasty in Open-Angle Glaucoma: What’s on? A Review of the LiteratureGloria Gambini0Matteo Mario Carlà1Tomaso Caporossi2Umberto De Vico3Alfonso Savastano4Antonio Baldascino5Clara Rizzo6Raphael Kilian7Stanislao Rizzo8Ophthalmology Unit, “Fondazione Policlinico Universitario A. Gemelli IRCCS”, 00168 Rome, ItalyOphthalmology Unit, “Fondazione Policlinico Universitario A. Gemelli IRCCS”, 00168 Rome, ItalyOphthalmology Unit, “Fondazione Policlinico Universitario A. Gemelli IRCCS”, 00168 Rome, ItalyOphthalmology Unit, “Fondazione Policlinico Universitario A. Gemelli IRCCS”, 00168 Rome, ItalyOphthalmology Unit, “Fondazione Policlinico Universitario A. Gemelli IRCCS”, 00168 Rome, ItalyOphthalmology Unit, “Fondazione Policlinico Universitario A. Gemelli IRCCS”, 00168 Rome, ItalyOphthalmology, Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, 56126 Pisa, ItalyOphthalmology Unit, University of Verona, 37134 Verona, ItalyOphthalmology Unit, “Fondazione Policlinico Universitario A. Gemelli IRCCS”, 00168 Rome, ItalyGlaucoma is the most common cause of permanent blindness in the world, caused by a progressive optic neuropathy. Patients with glaucoma are often treated with topical medicines therapy in order to reduce intra-ocular pressure (IOP). On the other hand, laser therapies, with the introduction of Argon Laser Trabeculoplasty (ALT) and successively with Selective Laser Trabeculoplasty (SLT), were reported to be effective in IOP control, with low adverse effect rates. In recent years, the micropulse laser, a subthreshold laser technology, was introduced with the goal of reducing side effects while maintaining the effectiveness of the laser treatments. Several studies focused on Micropulse Diode Laser Trabeculoplasty (MDLT) in open-angle glaucoma, to evaluate its effectiveness and possible side effects. Promising results were reported, but irradiation circumstances have not been standardized yet and its role as a substitute for previous laser techniques has yet to be defined. As a result, the goal of this review was to analyze the physical principles at the basis of MDLT and to frame it in the open-angle glaucoma management setting, highlighting the advantages and shortfalls of this technique.https://www.mdpi.com/2411-5150/6/1/8glaucomalaser trabeculoplastymicropulse trabeculoplastymicropulse lasersubthreshold lasermicropulse diode laser trabeculoplasty
spellingShingle Gloria Gambini
Matteo Mario Carlà
Tomaso Caporossi
Umberto De Vico
Alfonso Savastano
Antonio Baldascino
Clara Rizzo
Raphael Kilian
Stanislao Rizzo
Spotlight on MicroPulse Laser Trabeculoplasty in Open-Angle Glaucoma: What’s on? A Review of the Literature
Vision
glaucoma
laser trabeculoplasty
micropulse trabeculoplasty
micropulse laser
subthreshold laser
micropulse diode laser trabeculoplasty
title Spotlight on MicroPulse Laser Trabeculoplasty in Open-Angle Glaucoma: What’s on? A Review of the Literature
title_full Spotlight on MicroPulse Laser Trabeculoplasty in Open-Angle Glaucoma: What’s on? A Review of the Literature
title_fullStr Spotlight on MicroPulse Laser Trabeculoplasty in Open-Angle Glaucoma: What’s on? A Review of the Literature
title_full_unstemmed Spotlight on MicroPulse Laser Trabeculoplasty in Open-Angle Glaucoma: What’s on? A Review of the Literature
title_short Spotlight on MicroPulse Laser Trabeculoplasty in Open-Angle Glaucoma: What’s on? A Review of the Literature
title_sort spotlight on micropulse laser trabeculoplasty in open angle glaucoma what s on a review of the literature
topic glaucoma
laser trabeculoplasty
micropulse trabeculoplasty
micropulse laser
subthreshold laser
micropulse diode laser trabeculoplasty
url https://www.mdpi.com/2411-5150/6/1/8
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