INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS
A study was undertaken to investigate the role of placenta in transferring drugs containing bromine to the infant. 20 pregnant subjects were given bromine as KBr (500 mg/50 Kg weight) 10h before the delivery the bromine content of the serum in the mother and the child was estimated by neutron.. 13 l...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
1980-09-01
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| Series: | Acta Medica Iranica |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/135 |
| _version_ | 1818237558381871104 |
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| author | Z. Abedinzadeh Z.Khalkhali |
| author_facet | Z. Abedinzadeh Z.Khalkhali |
| author_sort | Z. Abedinzadeh |
| collection | DOAJ |
| description | A study was undertaken to investigate the role of placenta in transferring drugs containing bromine to the infant. 20 pregnant subjects were given bromine as KBr (500 mg/50 Kg weight) 10h before the delivery the bromine content of the serum in the mother and the child was estimated by neutron.. 13 lrradlated at 2xlO activation analysis. Samples were -2 -1 n em 5 for a period of one hour. A Ge (Li) detector connected to an 800 channel analyser 82 was used for measuring Br photopeaks. In 72% of the cases the distribution of bromine in both mother and child was equal, revealing a transfer across the placenta of the intaken drug. |
| first_indexed | 2024-12-12T12:27:40Z |
| format | Article |
| id | doaj.art-907fd58769074144a4930ee19de30792 |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-12-12T12:27:40Z |
| publishDate | 1980-09-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-907fd58769074144a4930ee19de307922022-12-22T00:24:30ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96941980-09-01223INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS Z. Abedinzadeh0 Z.Khalkhali1 A study was undertaken to investigate the role of placenta in transferring drugs containing bromine to the infant. 20 pregnant subjects were given bromine as KBr (500 mg/50 Kg weight) 10h before the delivery the bromine content of the serum in the mother and the child was estimated by neutron.. 13 lrradlated at 2xlO activation analysis. Samples were -2 -1 n em 5 for a period of one hour. A Ge (Li) detector connected to an 800 channel analyser 82 was used for measuring Br photopeaks. In 72% of the cases the distribution of bromine in both mother and child was equal, revealing a transfer across the placenta of the intaken drug.https://acta.tums.ac.ir/index.php/acta/article/view/135 |
| spellingShingle | Z. Abedinzadeh Z.Khalkhali INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS Acta Medica Iranica |
| title | INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS |
| title_full | INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS |
| title_fullStr | INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS |
| title_full_unstemmed | INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS |
| title_short | INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS |
| title_sort | investigation of the role of placenta in transfer of bromine containing drugs to infants |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/135 |
| work_keys_str_mv | AT zabedinzadeh investigationoftheroleofplacentaintransferofbrominecontainingdrugstoinfants AT zkhalkhali investigationoftheroleofplacentaintransferofbrominecontainingdrugstoinfants |