Epigallocatechin gallate (EGCG) suppresses lipopolysaccharide‐induced inflammatory bone resorption, and protects against alveolar bone loss in mice

Epigallocatechin gallate (EGCG) suppresses lipopolysaccharide‐induced inflammatory bone resorption, and protects against alveolar bone loss in mice

Epigallocatechin gallate (EGCG), a major polyphenol in green tea, possesses antioxidant properties and regulates various cell functions. Here, we examined the function of EGCG in inflammatory bone resorption. In calvarial organ cultures, lipopolysaccharide (LPS)‐induced bone resorption was clearly s...

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Bibliographic Details
Main Authors: Tsukasa Tominari, Chiho Matsumoto, Kenta Watanabe, Michiko Hirata, Florian M.W. Grundler, Chisato Miyaura, Masaki Inada
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:FEBS Open Bio
Subjects:
Epigallocatechin gallate
Lipopolysaccharide
Bone resorption
Periodontitis
Prostaglandin E
Osteoblasts
Online Access:https://doi.org/10.1016/j.fob.2015.06.003

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