Validation of differentially methylated microRNAs identified from an epigenome-wide association study; Sanger and next generation sequencing approaches
Abstract Objectives Altered DNA methylation and microRNA profiles are associated with diabetic kidney disease. This study compared different sequencing approaches to define the genetic and epigenetic architecture of sequences surrounding microRNAs associated with diabetic kidney disease. Results We...
Main Authors: | Laura J. Smyth, Alexander P. Maxwell, Katherine A. Benson, Jill Kilner, Gareth J. McKay, Amy Jayne McKnight |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-10-01
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Series: | BMC Research Notes |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13104-018-3872-x |
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