Antimicrobial Actions of Reactive Oxygen Species

ABSTRACT Everything should be as simple as it can be, but not simpler.—Attributed to Albert Einstein (1) IMPORTANCE Reactive oxygen species (ROS) are produced by host phagocytes and exert antimicrobial actions against a broad range of pathogens. The observable antimicrobial actions of ROS are highly...

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Main Author: Ferric C. Fang
Format: Article
Language:English
Published: American Society for Microbiology 2011-11-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00141-11
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author Ferric C. Fang
author_facet Ferric C. Fang
author_sort Ferric C. Fang
collection DOAJ
description ABSTRACT Everything should be as simple as it can be, but not simpler.—Attributed to Albert Einstein (1) IMPORTANCE Reactive oxygen species (ROS) are produced by host phagocytes and exert antimicrobial actions against a broad range of pathogens. The observable antimicrobial actions of ROS are highly dependent on experimental conditions. This perspective reviews recent controversies regarding ROS in Salmonella-phagocyte interactions and attempts to reconcile conflicting observations from different laboratories.
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spelling doaj.art-9084f2a1107f4ff6a0f5aaf54bb439da2022-12-21T19:08:55ZengAmerican Society for MicrobiologymBio2150-75112011-11-012510.1128/mBio.00141-11Antimicrobial Actions of Reactive Oxygen SpeciesFerric C. Fang0Departments of Laboratory Medicine and Microbiology, University of Washington School of Medicine, Seattle, Washington, USAABSTRACT Everything should be as simple as it can be, but not simpler.—Attributed to Albert Einstein (1) IMPORTANCE Reactive oxygen species (ROS) are produced by host phagocytes and exert antimicrobial actions against a broad range of pathogens. The observable antimicrobial actions of ROS are highly dependent on experimental conditions. This perspective reviews recent controversies regarding ROS in Salmonella-phagocyte interactions and attempts to reconcile conflicting observations from different laboratories.https://journals.asm.org/doi/10.1128/mBio.00141-11
spellingShingle Ferric C. Fang
Antimicrobial Actions of Reactive Oxygen Species
mBio
title Antimicrobial Actions of Reactive Oxygen Species
title_full Antimicrobial Actions of Reactive Oxygen Species
title_fullStr Antimicrobial Actions of Reactive Oxygen Species
title_full_unstemmed Antimicrobial Actions of Reactive Oxygen Species
title_short Antimicrobial Actions of Reactive Oxygen Species
title_sort antimicrobial actions of reactive oxygen species
url https://journals.asm.org/doi/10.1128/mBio.00141-11
work_keys_str_mv AT ferriccfang antimicrobialactionsofreactiveoxygenspecies