A randomized study of network-based perception learning in the treatment of amblyopia children
AIM: To compare the effectiveness of network-based perception learning (NBPL) and traditional training in the treatment of amblyopia children. METHODS: This randomized controlled clinical trial recruited 56 participants aged 4-12y with anisometropic and/or strabismic amblyopia. Participants were ran...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2022-05-01
|
| Series: | International Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/en_publish/2022/5/20220517.pdf |
| _version_ | 1818009462253813760 |
|---|---|
| author | Chang-Yue Zheng Wei Xu Shun-Qiang Wu Dong-Xu Han |
| author_facet | Chang-Yue Zheng Wei Xu Shun-Qiang Wu Dong-Xu Han |
| author_sort | Chang-Yue Zheng |
| collection | DOAJ |
| description | AIM: To compare the effectiveness of network-based perception learning (NBPL) and traditional training in the treatment of amblyopia children. METHODS: This randomized controlled clinical trial recruited 56 participants aged 4-12y with anisometropic and/or strabismic amblyopia. Participants were randomly divided into two groups: the NBPL group (n=28) who received patching and NBPL for 3mo, and the control group (n=28) who got 3mo of patching and traditional training. Best-corrected visual acuity (BCVA) in the amblyopic eye and stereoacuity were measured and compared at baseline, 1, 2, and 3mo post-randomization. RESULTS: There were no significant differences in age, gender ratio, and BCVA between the two groups at baseline. At 3mo, most patients gained lines (2 logMAR lines on average) of BCVA in both groups except one 11-year-old girl in the control group (P<0.05). But no significant difference in BCVA improvement of the amblyopic eye between the two groups was found (P=0.725), and amblyopia resolved (BCVA of 0.1 logMAR or better or within 1 logMAR line of the fellow eye) for 13 (46.4%) participants in both groups. The number of patients with improvement of stereoacuity was 25 and 13 in the NBPL group and control group (P=0.041), respectively, and a significant difference exists in the distribution of stereopsis at 3mo between the two groups (P=0.015). Besides, in patients with measurable stereopsis improvement degree and space for improvement in the two groups, the NBPL group also achieved better stereoscopic improvement than the control group (10/11 vs 4/11, P<0.05). CONCLUSION: The NBPL system has a significant effect on the improvement of BCVA and stereoacuity of amblyopia children and is better than traditional training in terms of stereoacuity improvement. Perceptual learning visual training may play a more important role in the treatment of amblyopia in the future. |
| first_indexed | 2024-04-14T05:43:10Z |
| format | Article |
| id | doaj.art-9089289890f04143864a53ec5330d464 |
| institution | Directory Open Access Journal |
| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-04-14T05:43:10Z |
| publishDate | 2022-05-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | International Journal of Ophthalmology |
| spelling | doaj.art-9089289890f04143864a53ec5330d4642022-12-22T02:09:22ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982022-05-0115580080610.18240/ijo.2022.05.1720220517A randomized study of network-based perception learning in the treatment of amblyopia childrenChang-Yue Zheng0Wei Xu1Shun-Qiang Wu2Dong-Xu Han3Wei Xu. Department of Ophthalmology, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, China. vvxuwei2021@163.comKey Laboratory of Myopia, Chinese Academy of Medical Sciences (Fudan University), Shanghai 200031, ChinaKey Laboratory of Myopia, Chinese Academy of Medical Sciences (Fudan University), Shanghai 200031, ChinaKey Laboratory of Myopia, Chinese Academy of Medical Sciences (Fudan University), Shanghai 200031, ChinaAIM: To compare the effectiveness of network-based perception learning (NBPL) and traditional training in the treatment of amblyopia children. METHODS: This randomized controlled clinical trial recruited 56 participants aged 4-12y with anisometropic and/or strabismic amblyopia. Participants were randomly divided into two groups: the NBPL group (n=28) who received patching and NBPL for 3mo, and the control group (n=28) who got 3mo of patching and traditional training. Best-corrected visual acuity (BCVA) in the amblyopic eye and stereoacuity were measured and compared at baseline, 1, 2, and 3mo post-randomization. RESULTS: There were no significant differences in age, gender ratio, and BCVA between the two groups at baseline. At 3mo, most patients gained lines (2 logMAR lines on average) of BCVA in both groups except one 11-year-old girl in the control group (P<0.05). But no significant difference in BCVA improvement of the amblyopic eye between the two groups was found (P=0.725), and amblyopia resolved (BCVA of 0.1 logMAR or better or within 1 logMAR line of the fellow eye) for 13 (46.4%) participants in both groups. The number of patients with improvement of stereoacuity was 25 and 13 in the NBPL group and control group (P=0.041), respectively, and a significant difference exists in the distribution of stereopsis at 3mo between the two groups (P=0.015). Besides, in patients with measurable stereopsis improvement degree and space for improvement in the two groups, the NBPL group also achieved better stereoscopic improvement than the control group (10/11 vs 4/11, P<0.05). CONCLUSION: The NBPL system has a significant effect on the improvement of BCVA and stereoacuity of amblyopia children and is better than traditional training in terms of stereoacuity improvement. Perceptual learning visual training may play a more important role in the treatment of amblyopia in the future.http://ies.ijo.cn/en_publish/2022/5/20220517.pdfamblyopiaperceptual learningstereoacuitybest-corrected visual acuity |
| spellingShingle | Chang-Yue Zheng Wei Xu Shun-Qiang Wu Dong-Xu Han A randomized study of network-based perception learning in the treatment of amblyopia children International Journal of Ophthalmology amblyopia perceptual learning stereoacuity best-corrected visual acuity |
| title | A randomized study of network-based perception learning in the treatment of amblyopia children |
| title_full | A randomized study of network-based perception learning in the treatment of amblyopia children |
| title_fullStr | A randomized study of network-based perception learning in the treatment of amblyopia children |
| title_full_unstemmed | A randomized study of network-based perception learning in the treatment of amblyopia children |
| title_short | A randomized study of network-based perception learning in the treatment of amblyopia children |
| title_sort | randomized study of network based perception learning in the treatment of amblyopia children |
| topic | amblyopia perceptual learning stereoacuity best-corrected visual acuity |
| url | http://ies.ijo.cn/en_publish/2022/5/20220517.pdf |
| work_keys_str_mv | AT changyuezheng arandomizedstudyofnetworkbasedperceptionlearninginthetreatmentofamblyopiachildren AT weixu arandomizedstudyofnetworkbasedperceptionlearninginthetreatmentofamblyopiachildren AT shunqiangwu arandomizedstudyofnetworkbasedperceptionlearninginthetreatmentofamblyopiachildren AT dongxuhan arandomizedstudyofnetworkbasedperceptionlearninginthetreatmentofamblyopiachildren AT changyuezheng randomizedstudyofnetworkbasedperceptionlearninginthetreatmentofamblyopiachildren AT weixu randomizedstudyofnetworkbasedperceptionlearninginthetreatmentofamblyopiachildren AT shunqiangwu randomizedstudyofnetworkbasedperceptionlearninginthetreatmentofamblyopiachildren AT dongxuhan randomizedstudyofnetworkbasedperceptionlearninginthetreatmentofamblyopiachildren |