KRASG12C mutant lung adenocarcinoma: unique biology, novel therapies and new challenges

KRASG12C mutant lung adenocarcinoma: unique biology, novel therapies and new challenges

KRAS mutant lung cancer is the most prevalent molecular subclass of adenocarcinoma (LUAD), which is a heterogenous group depending on the mutation-type which affects not only the function of the oncogene but affects the biological behavior of the cancer as well. Furthermore, KRAS mutation affects ra...

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Bibliographic Details
Main Authors: Judit Moldvay, József Tímár
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Pathology and Oncology Research
Subjects:
KRAS
lung adenocarcinoma
G12C mutation
sotorasib
adagrasib
Online Access:https://www.por-journal.com/articles/10.3389/pore.2023.1611580/full

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