Advances in Medical Wearable Biosensors: Design, Fabrication and Materials Strategies in Healthcare Monitoring
In the past decade, wearable biosensors have radically changed our outlook on contemporary medical healthcare monitoring systems. These smart, multiplexed devices allow us to quantify dynamic biological signals in real time through highly sensitive, miniaturized sensing platforms, thereby decentrali...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-12-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/27/1/165 |
| _version_ | 1797498266174095360 |
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| author | Sangeeth Pillai Akshaya Upadhyay Darren Sayson Bich Hong Nguyen Simon D. Tran |
| author_facet | Sangeeth Pillai Akshaya Upadhyay Darren Sayson Bich Hong Nguyen Simon D. Tran |
| author_sort | Sangeeth Pillai |
| collection | DOAJ |
| description | In the past decade, wearable biosensors have radically changed our outlook on contemporary medical healthcare monitoring systems. These smart, multiplexed devices allow us to quantify dynamic biological signals in real time through highly sensitive, miniaturized sensing platforms, thereby decentralizing the concept of regular clinical check-ups and diagnosis towards more versatile, remote, and personalized healthcare monitoring. This paradigm shift in healthcare delivery can be attributed to the development of nanomaterials and improvements made to non-invasive biosignal detection systems alongside integrated approaches for multifaceted data acquisition and interpretation. The discovery of new biomarkers and the use of bioaffinity recognition elements like aptamers and peptide arrays combined with the use of newly developed, flexible, and conductive materials that interact with skin surfaces has led to the widespread application of biosensors in the biomedical field. This review focuses on the recent advances made in wearable technology for remote healthcare monitoring. It classifies their development and application in terms of electrochemical, mechanical, and optical modes of transduction and type of material used and discusses the shortcomings accompanying their large-scale fabrication and commercialization. A brief note on the most widely used materials and their improvements in wearable sensor development is outlined along with instructions for the future of medical wearables. |
| first_indexed | 2024-03-10T03:31:01Z |
| format | Article |
| id | doaj.art-908e0d98a33a474fb3e25a5c603205c2 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T03:31:01Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-908e0d98a33a474fb3e25a5c603205c22023-11-23T11:57:43ZengMDPI AGMolecules1420-30492021-12-0127116510.3390/molecules27010165Advances in Medical Wearable Biosensors: Design, Fabrication and Materials Strategies in Healthcare MonitoringSangeeth Pillai0Akshaya Upadhyay1Darren Sayson2Bich Hong Nguyen3Simon D. Tran4McGill Craniofacial Tissue Engineering and Stem Cells Laboratory, Faculty of Dentistry, McGill University, 3640 University Street, Montreal, QC H3A 0C7, CanadaMcGill Craniofacial Tissue Engineering and Stem Cells Laboratory, Faculty of Dentistry, McGill University, 3640 University Street, Montreal, QC H3A 0C7, CanadaMcGill Craniofacial Tissue Engineering and Stem Cells Laboratory, Faculty of Dentistry, McGill University, 3640 University Street, Montreal, QC H3A 0C7, CanadaDepartment of Pediatrics, CHU Sainte Justine Hospital, Montreal, QC H3T 1C5, CanadaMcGill Craniofacial Tissue Engineering and Stem Cells Laboratory, Faculty of Dentistry, McGill University, 3640 University Street, Montreal, QC H3A 0C7, CanadaIn the past decade, wearable biosensors have radically changed our outlook on contemporary medical healthcare monitoring systems. These smart, multiplexed devices allow us to quantify dynamic biological signals in real time through highly sensitive, miniaturized sensing platforms, thereby decentralizing the concept of regular clinical check-ups and diagnosis towards more versatile, remote, and personalized healthcare monitoring. This paradigm shift in healthcare delivery can be attributed to the development of nanomaterials and improvements made to non-invasive biosignal detection systems alongside integrated approaches for multifaceted data acquisition and interpretation. The discovery of new biomarkers and the use of bioaffinity recognition elements like aptamers and peptide arrays combined with the use of newly developed, flexible, and conductive materials that interact with skin surfaces has led to the widespread application of biosensors in the biomedical field. This review focuses on the recent advances made in wearable technology for remote healthcare monitoring. It classifies their development and application in terms of electrochemical, mechanical, and optical modes of transduction and type of material used and discusses the shortcomings accompanying their large-scale fabrication and commercialization. A brief note on the most widely used materials and their improvements in wearable sensor development is outlined along with instructions for the future of medical wearables.https://www.mdpi.com/1420-3049/27/1/165biosensorswearable technologybiosensing materialsmedical monitoring |
| spellingShingle | Sangeeth Pillai Akshaya Upadhyay Darren Sayson Bich Hong Nguyen Simon D. Tran Advances in Medical Wearable Biosensors: Design, Fabrication and Materials Strategies in Healthcare Monitoring Molecules biosensors wearable technology biosensing materials medical monitoring |
| title | Advances in Medical Wearable Biosensors: Design, Fabrication and Materials Strategies in Healthcare Monitoring |
| title_full | Advances in Medical Wearable Biosensors: Design, Fabrication and Materials Strategies in Healthcare Monitoring |
| title_fullStr | Advances in Medical Wearable Biosensors: Design, Fabrication and Materials Strategies in Healthcare Monitoring |
| title_full_unstemmed | Advances in Medical Wearable Biosensors: Design, Fabrication and Materials Strategies in Healthcare Monitoring |
| title_short | Advances in Medical Wearable Biosensors: Design, Fabrication and Materials Strategies in Healthcare Monitoring |
| title_sort | advances in medical wearable biosensors design fabrication and materials strategies in healthcare monitoring |
| topic | biosensors wearable technology biosensing materials medical monitoring |
| url | https://www.mdpi.com/1420-3049/27/1/165 |
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