Natural Steroidal Lactone Induces G1/S Phase Cell Cycle Arrest and Intrinsic Apoptotic Pathway by Up-Regulating Tumor Suppressive miRNA in Triple-Negative Breast Cancer Cells
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with minimal treatment options. In the present work, Withaferin A (WA), a natural steroidal lactone found in <i>Withania somnifera</i> (Solanaceae), was studied to deduce the miRNA expression modulation mediat...
Main Authors: | Mohd Shuaib, Kumari Sunita Prajapati, Sanjay Gupta, Shashank Kumar |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-12-01
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Series: | Metabolites |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-1989/13/1/29 |
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